Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.56 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.50 |
| ▸ | PDPK1 | O15530 | 2/20 | 0.44 |
| ▸ | DHFR | P00374 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.40 |
| ▸ | HRH2 | P25021 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | NOS2 | P35228 | 1/20 | 0.39 |
| ▸ | CDK1 | P06493 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5748930 | 1.00 | KCNH2 (0.56) | KCNH2TLR8PDPK1DHFRKDM4E | |
| SCHEMBL5748502 | 1.00 | KCNH2 (0.56) | KCNH2TLR8PDPK1DHFRKDM4E | |
| SCHEMBL14043611 | 1.00 | KCNH2 (0.56) | KCNH2TLR8PDPK1DHFRKDM4E | |
| SCHEMBL3248683 | 0.98 | KCNH2 (0.53) | KCNH2TLR8PDPK1DHFRKDM4E | |
| SCHEMBL12514073 | 0.93 | TLR8 (0.53) | KCNH2TLR8PDPK1RAB9ASMN1; SMN2 | |
| SCHEMBL12336950 | 0.85 | TLR8 (0.47) | TLR8PDPK1KDM4EHRH3NOS2 | |
| SCHEMBL17053275 | 0.80 | KCNH2 (0.58) | KCNH2KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL22298878 | 0.80 | KCNH2 (0.58) | KCNH2KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL27769288 | 0.80 | KCNH2 (0.58) | KCNH2KDM4EALDH1A1HSD17B10HTR2A | |
| SCHEMBL27977748 | 0.80 | KCNH2 (0.58) | KCNH2KDM4EALDH1A1HSD17B10HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060293503-A1 | Polyaminopyridines and method for producing same | SUMITOMO SEIKA CHEMICALS CO., LTD (JP) | 2006-12-28 | — | — | US | disclosed |
| EP-1669390-A1 | POLYAMINOPYRIDINES AND METHOD FOR PRODUCING SAME | SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) | 2006-06-14 | — | — | EP | disclosed |