Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL553166 | 0.77 | KLKB1 (1.00) | KLKB1 | |
| SCHEMBL554102 | 0.77 | KLKB1 (1.00) | KLKB1 | |
| SCHEMBL554751 | 0.69 | KLKB1 (1.00) | KLKB1 | |
| SCHEMBL554454 | 0.69 | KLKB1 (1.00) | KLKB1 | |
| SCHEMBL553039 | 0.69 | KLKB1 (1.00) | KLKB1 | |
| SCHEMBL1912394 | 0.67 | KLKB1 (0.55) | KLKB1 | |
| SCHEMBL1912391 | 0.66 | KLKB1 (0.82) | KLKB1 | |
| SCHEMBL19589206 | 0.65 | KLKB1 (0.85) | KLKB1 | |
| SCHEMBL19589370 | 0.65 | KLKB1 (0.85) | KLKB1 | |
| SCHEMBL554752 | 0.64 | KLKB1 (1.00) | KLKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2601189-A1 | N-((6-AMINO-PYRIDIN-3-YL)METHYL)-HETEROARYL-CARBOXAMIDES AS INHIBITORS OF PLASMA KALLIKREIN | Novartis AG (CH) | 2013-06-12 | — | — | EP | claimed |
| WO-2012017020-A1 | N-((6-AMINO-PYRIDIN-3-YL)METHYL)-HETEROARYL-CARBOXAMIDES AS INHIBITORS OF PLASMA KALLIKREIN | NOVARTIS AG (CH) | 2012-02-09 | — | — | WO | claimed |
| EP-2601189-A1 | N-((6-AMINO-PYRIDIN-3-YL)METHYL)-HETEROARYL-CARBOXAMIDES AS INHIBITORS OF PLASMA KALLIKREIN | Novartis AG (CH) | 2013-06-12 | — | — | EP | disclosed |
| WO-2012017020-A1 | N-((6-AMINO-PYRIDIN-3-YL)METHYL)-HETEROARYL-CARBOXAMIDES AS INHIBITORS OF PLASMA KALLIKREIN | NOVARTIS AG (CH) | 2012-02-09 | — | — | WO | disclosed |