Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CETP | P11597 | 12/20 | 0.37 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.36 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.36 |
| ▸ | GRM5 | P41594 | 2/20 | 0.36 |
| ▸ | DAO | P14920 | 1/20 | 0.35 |
| ▸ | PIM1 | P11309 | 1/20 | 0.34 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.34 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5752987 | 0.89 | CETP (0.43) | CETPHCRTR1HCRTR2GRM5DAO | |
| SCHEMBL5751660 | 0.86 | CETP (0.44) | CETPHCRTR1HCRTR2GRM5DAO | |
| SCHEMBL5749830 | 0.85 | HCRTR1 (0.37) | CETPHCRTR1HCRTR2DAO | |
| SCHEMBL5750080 | 0.85 | CETP (0.46) | CETP | |
| SCHEMBL5754136 | 0.85 | MDM2 (0.39) | CETPHCRTR1HCRTR2DAOPIM1 | |
| SCHEMBL5751034 | 0.84 | CETP (0.43) | CETP | |
| SCHEMBL5752451 | 0.84 | CETP (0.37) | CETPHCRTR1HCRTR2DAOPIM1 | |
| SCHEMBL5752122 | 0.83 | CETP (0.37) | CETPHCRTR1HCRTR2GRM5DAO | |
| SCHEMBL5751191 | 0.83 | PIM1 (0.39) | CETPHCRTR1HCRTR2DAOPIM1 | |
| SCHEMBL5754437 | 0.82 | HCRTR1 (0.37) | CETPHCRTR1HCRTR2DAOPIM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6982348-B2 | Aminoethanol derivatives | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2006-01-03 | — | — | US | disclosed |
| US-20040127574-A1 | Aminoethanol derivatives | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2004-07-01 | — | — | US | disclosed |
| EP-1362846-A1 | AMINOETHANOL DERIVATIVES | Takeda Chemical Industries, Ltd. (JP) | 2003-11-19 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040127574-A1 | Aminoethanol derivatives | CETP, LCAT, MTTP | CETP 1/4885HCRTR1 1956/4885HCRTR2 1789/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.