Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IGF1R | P08069 | 10/20 | 0.55 |
| ▸ | KDR | P35968 | 3/20 | 0.52 |
| ▸ | EGFR | P00533 | 1/20 | 0.52 |
| ▸ | INSR | P06213 | 1/20 | 0.52 |
| ▸ | MET | P08581 | 1/20 | 0.52 |
| ▸ | CDK2 | P24941 | 1/20 | 0.52 |
| ▸ | TEK | Q02763 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | TNF | P01375 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.50 |
| ▸ | ABL1 | P00519 | 1/20 | 0.50 |
| ▸ | LCK | P06239 | 1/20 | 0.50 |
| ▸ | FYN | P06241 | 1/20 | 0.50 |
| ▸ | LTK | P29376 | 1/20 | 0.50 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1702765 | 0.81 | GRM4 (0.53) | IGF1RKDREGFRINSRMET | |
| SCHEMBL1703113 | 0.81 | CYP1A2 (0.57) | IGF1RKDREGFRINSRMET | |
| SCHEMBL1702057 | 0.80 | KDR (0.57) | IGF1RKDREGFRCYP1A2NPC1 | |
| SCHEMBL30033429 | 0.80 | KDR (0.57) | IGF1RKDREGFRCYP1A2NPC1 | |
| SCHEMBL5748170 | 0.80 | MAPK10 (0.56) | IGF1RKDRNPC1RAB9APOLB | |
| SCHEMBL24799998 | 0.79 | IGF1R (0.49) | IGF1RKDREGFRINSRMET | |
| SCHEMBL20362895 | 0.79 | IGF1R (0.49) | IGF1RKDREGFRINSRMET | |
| SCHEMBL5771191 | 0.79 | MAPK10 (0.51) | IGF1RKDRNPC1RAB9APOLB | |
| SCHEMBL1702273 | 0.79 | IGF1R (0.55) | IGF1RKDREGFRINSRMET | |
| SCHEMBL28220571 | 0.78 | TNF (0.59) | IGF1RKDREGFRINSRMET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060293503-A1 | Polyaminopyridines and method for producing same | SUMITOMO SEIKA CHEMICALS CO., LTD (JP) | 2006-12-28 | — | — | US | disclosed |
| EP-1669390-A1 | POLYAMINOPYRIDINES AND METHOD FOR PRODUCING SAME | SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) | 2006-06-14 | — | — | EP | disclosed |