Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 known ✓ | P03372 | 4/20 | 0.52 |
| ▸ | ESR2 known ✓ | Q92731 | 4/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.60 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA4 | P22748 | 1/20 | 0.42 |
| ▸ | CES2 | O00748 | 3/20 | 0.41 |
| ▸ | CES1 | P23141 | 3/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL29287419 | 1.00 | CYP3A4 (0.60) | CYP3A4TDP1ESR1ESR2CA2 | |
| Acetic Acid SCHEMBL132767 | 1.00 | CYP3A4 (0.60) | CYP3A4TDP1ESR1ESR2CA2 | |
| Acetic Acid SCHEMBL366510 | 1.00 | CYP3A4 (0.60) | CYP3A4TDP1ESR1ESR2CA2 | |
| Acetic Acid SCHEMBL7752539 | 0.98 | CYP3A4 (0.57) | CYP3A4TDP1ESR1ESR2CA2 | |
| Acetic Acid SCHEMBL3302716 | 0.98 | CYP3A4 (0.57) | CYP3A4TDP1ESR1ESR2CA2 | |
| Acetic Acid SCHEMBL28591790 | 0.98 | CYP3A4 (0.57) | CYP3A4TDP1ESR1ESR2CA2 | |
| Acetic Acid SCHEMBL3826322 | 0.95 | CYP3A4 (0.55) | CYP3A4TDP1ESR1ESR2CA2 | |
| Acetic Acid SCHEMBL8422529 | 0.95 | CYP3A4 (0.55) | CYP3A4TDP1ESR1ESR2CA2 | |
| Acetic Acid SCHEMBL8425843 | 0.95 | CYP3A4 (0.60) | CYP3A4TDP1ESR1ESR2CA2 | |
| Acetic Acid SCHEMBL8693165 | 0.95 | CYP3A4 (0.60) | CYP3A4TDP1ESR1ESR2CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 508 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-121574134-A | Preparation method of treasipril and salt thereof | 济南圣泉集团股份有限公司 | 2026-02-27 | — | — | CN | claimed |
| CN-120058707-A | Preparation method of PARP inhibitor and intermediate thereof | 湖北生物医药产业技术研究院有限公司 | 2025-05-30 | — | — | CN | claimed |
| CN-120037987-A | Aryl phosphine oxide ligand copper-based catalyst, preparation method thereof and application thereof in hydrochlorination of acetylene | 贵州重力科技环保股份有限公司 | 2025-05-27 | — | — | CN | claimed |
| CN-119912431-A | Preparation method and control of Abeli impurity A | 江苏天士力帝益药业有限公司 | 2025-05-02 | — | — | CN | claimed |
| CN-119490978-B | Modified starch-based surfactant and preparation method and application thereof | 佛山市益境环保科技有限公司温州分公司 | 2025-04-15 | — | — | CN | claimed |
| CN-119264184-B | Preparation method of dideoxy ring-opened ribonucleotide triphosphate and intermediate | 天津奥利芙生物技术有限公司 | 2025-03-28 | — | — | CN | claimed |
| CN-119708491-A | Polydisulfide polymer material containing hydroxy ester group and preparation method thereof | 衢州化工新材料创新研究院 | 2025-03-28 | — | — | CN | claimed |
| CN-119663360-A | Supported catalyst for synthesizing dimethyl carbonate by electrocatalytic carbon dioxide, preparation method and application | 北京理工大学深圳汽车研究院(电动车辆国家工程实验室深圳研究院) | 2025-03-21 | — | — | CN | claimed |
| CN-119490978-A | Modified starch-based surfactant and preparation method and application thereof | 佛山市益境环保科技有限公司温州分公司 | 2025-02-21 | — | — | CN | claimed |
| WO-2025011547-A1 | METHOD FOR OBTAINING ON-DNA AROMATIC COMPOUND VIA SUZUKI COUPLING REACTION AND USE THEREOF | 晶泰智药技术(上海)有限公司 | 2025-01-16 | — | — | WO | claimed |
| CN-103951612-A | Oxime ether acetate compound and preparation method and application thereof | UNIV ZHEJIANG TECHNOLOGY | 2014-07-30 | — | — | CN | claimed |
| CN-102951979-B | Preparation method of 2-substitutional vinyl alcohol formate derivative | UNIV TIANJIN | 2014-07-09 | — | — | CN | claimed |
| CN-103910670-A | Methoxy carbamate compound and preparation method and application thereof | UNIV ZHEJIANG TECHNOLOGY | 2014-07-09 | — | — | CN | claimed |
| CN-103768754-A | Fire-extinguishment composition containing unsaturated hydrocarbon compounds and derivatives thereof | XI AN JIAN RUI SAFETY EMERGENCY EQUIPMENT LTD LIABILITY COMPANY | 2014-05-07 | — | — | CN | claimed |
| CN-102989508-A | Synthesizing method and application of polymer microsphere immobilized palladium nanometer particles | UNIV PEKING SHENZHEN GRAD SCHO | 2013-03-27 | — | — | CN | claimed |
| CN-102951979-A | Preparation method of 2-substitutional vinyl alcohol formate derivative | UNIV TIANJIN | 2013-03-06 | — | — | CN | claimed |
| CN-102140062-B | Method for preparing 2,5-dimethyl phenylacetic acid | LIANHE CHEMICAL TECHNOLOGY CO LTD | 2012-11-14 | — | — | CN | claimed |
| CN-102746225-A | Preparation method of 2-alkyl-3,4-disubstituted isoquinolyl-1(2H)-ketone derivative | UNIV TIANJIN | 2012-10-24 | — | — | CN | claimed |
| CN-102746224-A | Preparation method of 2-aryl-3,4-disubstituted isoquinolyl-1(2H)-ketone derivative | UNIV TIANJIN | 2012-10-24 | — | — | CN | claimed |
| CN-102140062-A | Method for preparing 2,5-dimethyl phenylacetic acid | LIANHE CHEMICAL TECHNOLOGY CO LTD | 2011-08-03 | — | — | CN | claimed |