Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 9/20 | 0.52 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.40 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5750940 | 0.93 | KCNH2 (0.54) | KCNH2MCHR1ADRA1DADRA1AADRA1B | |
| SCHEMBL5777234 | 0.87 | KCNH2 (0.52) | KCNH2MCHR1ADRA1DADRA1AADRA1B | |
| SCHEMBL5764668 | 0.86 | KCNH2 (0.53) | KCNH2MCHR1 | |
| SCHEMBL14573143 | 0.84 | KCNH2 (0.55) | KCNH2MCHR1 | |
| SCHEMBL5751255 | 0.83 | KCNH2 (0.38) | KCNH2 | |
| SCHEMBL5775582 | 0.82 | KCNH2 (0.58) | KCNH2 | |
| SCHEMBL5764517 | 0.81 | KCNH2 (0.58) | KCNH2 | |
| SCHEMBL14573144 | 0.79 | KCNH2 (0.61) | KCNH2 | |
| SCHEMBL5749375 | 0.77 | KCNH2 (0.59) | KCNH2 | |
| SCHEMBL5747711 | 0.76 | KCNH2 (0.38) | KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1419155-B1 | PIPERIDINE DERIVATIVES AS ANTIBACTERIAL AGENTS | SMITHKLINE BEECHAM PLC (GB) | 2006-11-08 | — | — | EP | claimed |