Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 2/20 | 0.46 |
| ▸ | TLR8 | Q9NR97 | 5/20 | 0.43 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.42 |
| ▸ | BID | P55957 | 3/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.40 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.40 |
| ▸ | BAK1 | Q16611 | 2/20 | 0.40 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.40 |
| ▸ | PPARA | Q07869 | 2/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | EP300 | Q09472 | 1/20 | 0.40 |
| ▸ | KAT2A | Q92830 | 1/20 | 0.40 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.40 |
| ▸ | KAT5 | Q92993 | 1/20 | 0.40 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.38 |
| ▸ | OXER1 | Q8TDS5 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2251965 | 1.00 | KCNH2 (0.46) | KCNH2TLR8LIPGBIDMCL1 | |
| SCHEMBL2256150 | 1.00 | KCNH2 (0.46) | KCNH2TLR8LIPGBIDMCL1 | |
| SCHEMBL2254067 | 0.94 | BCHE (0.39) | KCNH2TLR8LIPGALOX5PTGS2 | |
| SCHEMBL2253305 | 0.88 | TLR8 (0.43) | KCNH2TLR8LIPGBIDMCL1 | |
| SCHEMBL5748971 | 0.88 | TLR8 (0.43) | KCNH2TLR8LIPGBIDMCL1 | |
| SCHEMBL2253157 | 0.88 | TLR8 (0.43) | KCNH2TLR8LIPGBIDMCL1 | |
| SCHEMBL7835007 | 0.87 | NQO2 (0.35) | MTNR1A | |
| SCHEMBL1973584 | 0.86 | TLR8 (0.42) | KCNH2TLR8LIPGBIDMCL1 | |
| SCHEMBL2256018 | 0.84 | TLR8 (0.41) | KCNH2TLR8LIPGBIDMCL1 | |
| SCHEMBL2252218 | 0.84 | TLR8 (0.41) | KCNH2TLR8LIPGBIDMCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060293503-A1 | Polyaminopyridines and method for producing same | SUMITOMO SEIKA CHEMICALS CO., LTD (JP) | 2006-12-28 | — | — | US | disclosed |
| EP-1669390-A1 | POLYAMINOPYRIDINES AND METHOD FOR PRODUCING SAME | SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) | 2006-06-14 | — | — | EP | disclosed |