Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 9/20 | 0.47 |
| ▸ | PTGER4 | P35408 | 5/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.41 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.41 |
| ▸ | CTSL | P07711 | 3/20 | 0.40 |
| ▸ | CTSB | P07858 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5651596 | 0.88 | HDAC1 (0.47) | HDAC1PTGER4HDAC4HDAC6HDAC3 | |
| SCHEMBL5653169 | 0.86 | HDAC1 (0.47) | HDAC1PTGER4HDAC4HDAC6HDAC3 | |
| SCHEMBL5655045 | 0.83 | PTGER4 (0.52) | HDAC1PTGER4HDAC4HDAC6 | |
| SCHEMBL5801097 | 0.82 | ANPEP (0.52) | HDAC1HDAC4HDAC6HDAC3HDAC7 | |
| SCHEMBL5654879 | 0.81 | HDAC1 (0.49) | HDAC1PTGER4HDAC4HDAC6 | |
| SCHEMBL5652247 | 0.80 | HDAC1 (0.49) | HDAC1PTGER4HDAC4HDAC6 | |
| SCHEMBL5651859 | 0.80 | HDAC1 (0.47) | HDAC1PTGER4HDAC4HDAC6 | |
| SCHEMBL5653483 | 0.80 | HDAC1 (0.47) | HDAC1PTGER4HDAC4HDAC6 | |
| SCHEMBL5654516 | 0.80 | HDAC1 (0.47) | HDAC1PTGER4HDAC6 | |
| SCHEMBL5654551 | 0.79 | HDAC1 (0.47) | HDAC1PTGER4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1697337-A2 | ORNITHINE DERIVATIVES AS PROSTAGLANDIN-E2-AGONISTS OR ANTAGONISTS | Astellas Pharma Inc. (JP) | 2006-09-06 | — | — | EP | disclosed |
| WO-2005061475-A2 | ORNITHINE DERIVATIVES AS PROSTAGLANDIN E2 AGONISTS OR ANTAGONISTS | ASTELLAS PHARMA INC. (JP) | 2005-07-07 | — | — | WO | disclosed |