Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A1 | P43005 | 2/20 | 0.44 |
| ▸ | PPARG | P37231 | 5/20 | 0.38 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | PPARA | Q07869 | 4/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.32 |
| ▸ | CTSS | P25774 | 1/20 | 0.32 |
| ▸ | CTSK | P43235 | 1/20 | 0.32 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.32 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | CTSD | P07339 | 1/20 | 0.32 |
| ▸ | BACE1 | P56817 | 1/20 | 0.32 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5751666 | 0.90 | SLC1A1 (0.43) | SLC1A1PPARGKMT2AMEN1PPARA | |
| SCHEMBL5754855 | 0.82 | SLC1A1 (0.48) | SLC1A1PPARGKMT2APPARAPTGS2 | |
| SCHEMBL5752317 | 0.81 | SLC1A1 (0.43) | SLC1A1PPARGKMT2APPARAKDM4E | |
| SCHEMBL5752844 | 0.81 | SLC1A1 (0.45) | SLC1A1PPARGPPARAPTGS2KDM4E | |
| SCHEMBL5751805 | 0.78 | SLC1A1 (0.47) | SLC1A1PPARGKMT2AMEN1PPARA | |
| SCHEMBL5752490 | 0.78 | SLC1A1 (0.44) | SLC1A1PPARGKMT2APPARAKDM4E | |
| SCHEMBL5749740 | 0.77 | SLC1A1 (0.43) | SLC1A1PPARGPPARAKDM4EALDH1A1 | |
| SCHEMBL5748762 | 0.76 | CETP (0.46) | SLC1A1PPARGPPARA | |
| SCHEMBL5751725 | 0.76 | SLC1A1 (0.44) | SLC1A1PPARGPPARAKDM4EALDH1A1 | |
| SCHEMBL5753245 | 0.76 | SLC1A1 (0.44) | SLC1A1PPARGPPARATRPM8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6982348-B2 | Aminoethanol derivatives | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2006-01-03 | — | — | US | disclosed |
| US-20040127574-A1 | Aminoethanol derivatives | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2004-07-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040127574-A1 | Aminoethanol derivatives | CETP, LCAT, MTTP | SLC1A1 343/4885PPARG 905/4885RIPK1 4659/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.