Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MDM2 | Q00987 | 4/20 | 0.41 |
| ▸ | GRM5 | P41594 | 4/20 | 0.38 |
| ▸ | TACR1 | P25103 | 2/20 | 0.37 |
| ▸ | DAO | P14920 | 3/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | CES2 | O00748 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5752541 | 1.00 | MDM2 (0.41) | MDM2GRM5TACR1DAOMAOB | |
| SCHEMBL5751029 | 0.91 | MDM2 (0.47) | MDM2GRM5DAOGAA | |
| SCHEMBL5750184 | 0.90 | MDM2 (0.40) | MDM2GRM5CES2GAA | |
| SCHEMBL5750594 | 0.90 | MAOB (0.43) | GRM5DAOMAOBCES2PPARG | |
| SCHEMBL5750910 | 0.89 | MDM2 (0.43) | MDM2GRM5DAOMAOBCES2 | |
| SCHEMBL5754087 | 0.89 | MDM2 (0.40) | MDM2GRM5DAOGAA | |
| SCHEMBL5750557 | 0.87 | MAOB (0.39) | GRM5DAOMAOBCES2PPARG | |
| SCHEMBL5749586 | 0.86 | GRM5 (0.44) | GRM5 | |
| SCHEMBL5753935 | 0.86 | GRM5 (0.40) | MDM2GRM5DAOMAOBCES2 | |
| SCHEMBL5751179 | 0.86 | DAO (0.43) | GRM5TACR1DAO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6982348-B2 | Aminoethanol derivatives | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2006-01-03 | — | — | US | disclosed |
| US-20040127574-A1 | Aminoethanol derivatives | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2004-07-01 | — | — | US | disclosed |
| EP-1362846-A1 | AMINOETHANOL DERIVATIVES | Takeda Chemical Industries, Ltd. (JP) | 2003-11-19 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040127574-A1 | Aminoethanol derivatives | CETP, LCAT, MTTP | MDM2 3868/4885GRM5 2869/4885TACR1 2291/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.