SCHEMBL57525

SCHEMBL57525

c1ccc(-c2cccc3ccccc23)nc1

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 7/20 0.63
TP53 P04637 5/20 0.63
SMN1; SMN2 Q16637 4/20 0.63
ALDH1A1 P00352 4/20 0.63
HPGD P15428 4/20 0.63
MAPT P10636 3/20 0.63
NPC1 O15118 3/20 0.63
HSD17B10 Q99714 3/20 0.63
MAPK1 P28482 2/20 0.63
TGFBR1 P36897 1/20 0.58
HTR2C P28335 3/20 0.57
LMNA P02545 3/20 0.56
CCR1 P32246 2/20 0.56
CCR5 P51681 2/20 0.56
CCR8 P51685 2/20 0.56
TDP1 Q9NUW8 2/20 0.56
ALOX15 P16050 2/20 0.56
HTT P42858 2/20 0.56
L3MBTL1 Q9Y468 2/20 0.56
ALPL P05186 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29484714 1.00 KDM4E (0.63) KDM4ETP53SMN1; SMN2ALDH1A1HPGD
SCHEMBL31607260 1.00 KDM4E (0.63) KDM4ETP53SMN1; SMN2ALDH1A1HPGD
SCHEMBL31473547 1.00 KDM4E (0.63) KDM4ETP53SMN1; SMN2ALDH1A1HPGD
Hydrochloric Acid SCHEMBL29042408 0.98 KDM4E (0.61) KDM4ETP53SMN1; SMN2ALDH1A1HPGD
Bromide SCHEMBL27866709 0.98 KDM4E (0.61) KDM4ETP53SMN1; SMN2ALDH1A1HPGD
SCHEMBL20237398 0.98 KDM4E (0.61) KDM4ETP53SMN1; SMN2ALDH1A1HPGD
SCHEMBL30302967 0.98 KDM4E (0.61) KDM4ETP53SMN1; SMN2ALDH1A1HPGD
SCHEMBL26259997 0.91 KDM4E (0.62) KDM4ETP53SMN1; SMN2ALDH1A1HPGD
Quinoxaline SCHEMBL27442177 0.91 KDM4E (0.55) KDM4ETP53SMN1; SMN2ALDH1A1HPGD
SCHEMBL4242615 0.90 KDM4E (0.54) KDM4ETP53SMN1; SMN2ALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 7164 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025101127-A1 CONJUGATED OLIGOELECTROLYTES AND METHODS STAINING MITOCHONDRIA THEREOF NATIONAL UNIVERSITY OF SINGAPORE (SG) 2025-05-15 WO claimed
US-20240124770-A1 COMPOUND, GUEST MATERIAL OF LIGHT-EMITTING LAYER, ORGANIC ELECTROLUMINESCENT DEVICE, AND DISPLAY DEVICE BEIJING NORMAL UNIVERSITY (CN) 2024-04-18 US claimed
CN-115605529-B Photochromic polydiorganosiloxane vinyl cross-linking agent 爱尔康公司 2024-03-26 CN claimed
CN-117729917-A Combination therapy using AKR1C3 activating compounds and immune checkpoint inhibitors 深圳艾欣达伟医药科技有限公司 2024-03-19 CN claimed
CN-115160354-A Method for efficiently synthesizing aryl silicon compound 南阳师范学院 2022-10-11 CN claimed
WO-2022166889-A1 COMPOUND, GUEST MATERIAL OF LIGHT-EMITTING LAYER, ORGANIC ELECTROLUMINESCENT DEVICE, AND DISPLAY DEVICE 北京师范大学 2022-08-11 WO claimed
CN-109790407-B Printing ink composition, preparation method and application thereof 广州华睿光电材料有限公司 2021-12-07 CN claimed
CN-109790406-B Composition for printing electronic device and preparation method and application thereof 广州华睿光电材料有限公司 2021-12-07 CN claimed
CN-112979713-A Compound, light-emitting layer guest material, organic electroluminescent device and display device 北京师范大学 2021-06-18 CN claimed
US-10955395-B2 Ruthenium complex for use in nitrite detection CITY UNIVERSITY OF HONG KONG (HK) 2021-03-23 US claimed
WO-1998010473-A1 ELECTRODE DEPOSITION FOR ORGANIC LIGHT-EMITTING DEVICES CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) 1998-03-12 WO claimed
CN-1173923-A Retroreflective signage articles, kits for producing same, and methods of making signage articles MINNESOTA MINING & MFG (US) 1998-02-18 CN claimed
US-5706133-A Retroreflective signage articles, kits for producing same, and methods of making signage articles MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1998-01-06 US claimed
EP-0808471-A1 RETROREFLECTIVE SIGNAGE ARTICLES, KITS FOR PRODUCING SAME, AND METHODS OF MAKING SIGNAGE ARTICLES MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1997-11-26 EP claimed
US-5611915-A Process for removal of heteroatoms under reducing conditions in supercritical water EXXON RESEARCH AND ENGINEERING COMPANY (US) 1997-03-18 US claimed
WO-1996024867-A1 RETROREFLECTIVE SIGNAGE ARTICLES, KITS FOR PRODUCING SAME, AND METHODS OF MAKING SIGNAGE ARTICLES MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1996-08-15 WO claimed
EP-0671454-A2 Process for removal of heteroatoms EXXON RESEARCH AND ENGINEERING COMPANY (US) 1995-09-13 EP claimed
EP-0295034-B1 Hydrolyzable compounds which release electron transfer agents and analytical use of same EASTMAN KODAK CO (US) 1994-08-31 EP claimed
US-4952495-A CLEAVING BLOCKED MOIETIES TO PRODUCE REDUCIBLE AND OXIDIZABLE COMPOUNDS; DETECTING HYDROLYTIC ENZYMES; QUINONE AND PHENAZINE COMPONENTS EASTMAN KODAK COMPANY (US) 1990-08-28 US claimed
EP-0295034-A2 Hydrolyzable compounds which release electron transfer agents and analytical use of same CLINICAL DIAGNOSTIC SYSTEMS, INC. (US) 1988-12-14 EP claimed