Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 8/20 | 0.53 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.47 |
| ▸ | DRD4 | P21917 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5755670 | 0.86 | SLC2A1 (0.52) | SLC2A1KCNH2 | |
| SCHEMBL5757572 | 0.86 | SLC2A1 (0.52) | SLC2A1KCNH2 | |
| SCHEMBL5755852 | 0.85 | SLC2A1 (0.54) | SLC2A1KCNH2 | |
| SCHEMBL5755845 | 0.85 | SLC2A1 (0.54) | SLC2A1KCNH2 | |
| SCHEMBL5755849 | 0.85 | SLC2A1 (0.54) | SLC2A1KCNH2 | |
| SCHEMBL5759496 | 0.85 | SLC2A1 (0.60) | SLC2A1KCNH2DRD4 | |
| SCHEMBL5759487 | 0.85 | SLC2A1 (0.60) | SLC2A1KCNH2DRD4 | |
| SCHEMBL5758574 | 0.85 | SLC2A1 (0.60) | SLC2A1KCNH2DRD4 | |
| SCHEMBL5757000 | 0.80 | SLC2A1 (0.58) | SLC2A1KCNH2DRD4 | |
| SCHEMBL5760232 | 0.80 | SLC2A1 (0.58) | SLC2A1KCNH2DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1343765-B1 | QUINOLINES AND NITROGENATED DERIVATIVES THEREOF SUBSTITUTED IN 4-POSITION BY A PIPERAZINE-CONTAINING MOIETY AND THEIR USE AS ANTIBACTERIAL AGENTS | SMITHKLINE BEECHAM PLC (GB) | 2006-11-22 | — | — | EP | claimed |