Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 1/20 | 0.67 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | APP | P05067 | 1/20 | 0.52 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.50 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.50 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.50 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.50 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.50 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.50 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15854220 | 0.86 | KMT2A (0.51) | EGFRHTTMAPTRAB9AL3MBTL1 | |
| SCHEMBL10102731 | 0.85 | POLB (0.58) | EGFRMAPTRAB9AL3MBTL1HDAC3 | |
| SCHEMBL14490544 | 0.85 | HDAC3 (0.55) | EGFRRAB9AL3MBTL1HDAC3HDAC4 | |
| Hydrochloric Acid SCHEMBL17219701 | 0.85 | KMT2A (0.50) | EGFRHTTMAPTRAB9AL3MBTL1 | |
| Hydrochloric Acid SCHEMBL17219703 | 0.85 | KMT2A (0.50) | EGFRHTTMAPTRAB9AL3MBTL1 | |
| SCHEMBL8756757 | 0.85 | EGFR (0.68) | EGFRZDHHC2HTTMAPTAPP | |
| SCHEMBL8756769 | 0.85 | EGFR (0.68) | EGFRZDHHC2HTTMAPTAPP | |
| SCHEMBL8756763 | 0.85 | EGFR (0.68) | EGFRZDHHC2HTTMAPTAPP | |
| SCHEMBL15854222 | 0.84 | KDM4E (0.49) | EGFRHTTMAPTRAB9AL3MBTL1 | |
| SCHEMBL11105977 | 0.84 | EGFR (0.67) | EGFRZDHHC2HTTMAPTAPP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1659881-A2 | NOVEL FLAVORS, FLAVOR MODIFIERS, TASTANTS, TASTE ENHANCERS, UMAMI OR SWEET TASTANTS, AND/OR ENHANCERS AND USE THEREOF | Senomyx Inc. (US) | 2006-05-31 | — | — | EP | disclosed |
| WO-2005041684-A2 | NOVEL FLAVORS, FLAVOR MODIFIERS, TASTANTS, TASTE ENHANCERS, UMAMI OR SWEET TASTANTS, AND/OR ENHANCERS AND USE THEREOF | SENOMYX INC. (US) | 2005-05-12 | — | — | WO | disclosed |