⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7567480 | 0.70 | — | — | |
| Ammonia Solution, Strong SCHEMBL28121424 | 0.70 | — | — | |
| SCHEMBL9178861 | 0.70 | — | — | |
| SCHEMBL11479452 | 0.70 | — | — | |
| Ammonia Solution, Strong SCHEMBL28635407 | 0.68 | — | — | |
| Hydrochloric Acid SCHEMBL28391738 | 0.67 | — | — | |
| SCHEMBL16312835 | 0.67 | — | — | |
| SCHEMBL5198377 | 0.67 | — | — | |
| SCHEMBL6355934 | 0.67 | — | — | |
| SCHEMBL243254 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103492377-B | As the triazolopyridine compounds of PIM kinase inhibitor | ARRAY BIOPHARMA INC. (US) | 2016-04-20 | — | — | CN | disclosed |
| CN-105473585-A | Piperidinecarboxylic acid derivatives as fungicides | BAYER CROPSCIENCE AG | 2016-04-06 | — | — | CN | disclosed |
| CN-101124199-B | 5-substituted-2-phenylamino-benzamides as MEK inhibiting substances | CHUGAI PHARMACEUTICAL CO.,LTD. (JP) | 2011-12-14 | — | — | CN | disclosed |
| CN-101124199-A | 5-substituted-2-phenylamino-benzamides as MEK inhibiting substances | CHUGAI PHARMACEUTICAL CO LTD (JP) | 2008-02-13 | — | — | CN | disclosed |
| EP-1660448-A1 | INDOL-2-AMIDES AS GLYCOGEN PHOSPHORYLASE INHIBITORS | Astrazeneca AB (SE) | 2006-05-31 | — | — | EP | disclosed |
| EP-1656136-A1 | HETEROCYCLIC AMIDE DERIVATIVES WHICH POSSESS GLYCOGEN PHOSPHORYLASE INHIBITORY ACTIVITY | AstraZeneca AB (SE) | 2006-05-17 | — | — | EP | disclosed |
| WO-2005018637-A1 | HETEROCYCLIC AMIDE DERIVATIVES WHICH POSSESS GLYCOGEN PHOSPHORYLASE INHIBITORY ACTIVITY | ASTRAZENECA AB (SE) | 2005-03-03 | — | — | WO | disclosed |
| WO-2005019172-A1 | INDOL-2-AMIDES AS GLYCOGEN PHOSPHORYLASE INHIBITORS | ASTRAZENECA AB (SE) | 2005-03-03 | — | — | WO | disclosed |