Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 20/20 | 0.51 |
| ▸ | F10 | P00742 | 2/20 | 0.51 |
| ▸ | PRSS1 | P07477 | 12/20 | 0.51 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.50 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL5124943 | 0.95 | F2 (0.48) | F2F10PRSS1PRSS2PRSS3 | |
| SCHEMBL5753472 | 0.93 | F2 (0.55) | F2F10PRSS1PRSS2PRSS3 | |
| Trifluoroacetic Acid SCHEMBL5116965 | 0.88 | F2 (0.53) | F2F10PRSS1PRSS2PRSS3 | |
| SCHEMBL5754215 | 0.88 | F2 (0.56) | F2F10PRSS1PRSS2PRSS3 | |
| SCHEMBL14131986 | 0.88 | F2 (0.54) | F2F10PRSS1PRSS2PRSS3 | |
| SCHEMBL5755919 | 0.88 | F2 (0.54) | F2F10PRSS1PRSS2PRSS3 | |
| SCHEMBL5755847 | 0.87 | F2 (0.52) | F2F10PRSS1PRSS2PRSS3 | |
| SCHEMBL5755992 | 0.87 | F2 (0.62) | F2F10PRSS1PRSS2PRSS3 | |
| SCHEMBL5755807 | 0.87 | F2 (0.56) | F2F10PRSS1PRSS2PRSS3 | |
| SCHEMBL5753975 | 0.87 | F2 (0.57) | F2F10PRSS1PRSS2PRSS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1036063-B1 | HETEROARYL AMINOGUANIDINES AND ALKOXYGUANIDINES AND THEIR USE AS PROTEASE INHIBITORS | ORTHO MCNEIL PHARM INC (US) | 2006-11-02 | — | — | EP | claimed |
| US-7402586-B2 | Heteroaryl aminoguanidines and alkoxyguanidines and their use as protease inhibitors | ORTHO-MCNEIL PHARMACEUTICAL, INC. (US) | 2008-07-22 | — | — | US | disclosed |
| US-7402586-B2 | Heteroaryl aminoguanidines and alkoxyguanidines and their use as protease inhibitors | ORTHO-MCNEIL PHARMACEUTICAL, INC. (US) | 2008-07-22 | — | — | US | disclosed |