⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4603678 | 1.00 | — | — | |
| SCHEMBL4800307 | 1.00 | — | — | |
| SCHEMBL4603681 | 1.00 | — | — | |
| SCHEMBL17674956 | 1.00 | — | — | |
| SCHEMBL17674957 | 1.00 | — | — | |
| SCHEMBL5754268 | 1.00 | — | — | |
| SCHEMBL4800314 | 1.00 | — | — | |
| Iodide SCHEMBL11744028 | 0.96 | — | — | |
| Iodide SCHEMBL11744023 | 0.96 | — | — | |
| Hydrochloric Acid SCHEMBL4474998 | 0.96 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1485351-A4 | PROCESS FOR THE MANUFACTURE OF OPTICALLY ACTIVE 3-SUBSTITUTED LACTAMS BY ASYMMETRIC HYDROGENATION OF 3-ALKYLIDENELACTAMS | BRISTOL MYERS SQUIBB CO (US) | 2006-05-03 | — | — | EP | disclosed |
| EP-1485351-A2 | PROCESS FOR THE MANUFACTURE OF OPTICALLY ACTIVE 3-SUBSTITUTED LACTAMS BY ASYMMETRIC HYDROGENATION OF 3-ALKYLIDENELACTAMS | Bristol-Myers Squibb Company (US) | 2004-12-15 | — | — | EP | disclosed |
| WO-2003079975-A2 | PROCESS FOR THE MANUFACTURE OF OPTICALLY ACTIVE 3-SUBSTITUTED LACTAMS BY ASYMMETRIC HYDROGENATION OF 3-ALKYLIDENELACTAMS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2003-10-02 | — | — | WO | disclosed |