Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 20/20 | 0.88 |
| ▸ | CYP2C9 | P11712 | 6/20 | 0.88 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.88 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5202512 | 0.94 | ELANE (1.00) | ELANECYP2C9CYP3A4 | |
| SCHEMBL2885094 | 0.91 | ELANE (0.92) | ELANECYP2C9CYP3A4 | |
| SCHEMBL2886592 | 0.89 | ELANE (0.73) | ELANECYP2C9CYP3A4 | |
| SCHEMBL2881464 | 0.89 | ELANE (0.73) | ELANECYP2C9CYP3A4 | |
| SCHEMBL2886045 | 0.89 | ELANE (0.84) | ELANECYP2C9CYP3A4 | |
| SCHEMBL8343245 | 0.88 | ELANE (0.86) | ELANECYP2C9CYP3A4 | |
| SCHEMBL8344191 | 0.88 | ELANE (0.86) | ELANECYP2C9CYP3A4 | |
| SCHEMBL5473659 | 0.88 | ELANE (0.71) | ELANECYP2C9CYP3A4 | |
| SCHEMBL5752067 | 0.88 | ELANE (0.69) | ELANECYP2C9CYP3A4 | |
| SCHEMBL2902763 | 0.88 | ELANE (0.80) | ELANECYP2C9CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7199136-B2 | 1,4-dihydro-1,4-diphenylpyridine derivatives | BAYER HEALTHCARE AG (DE) | 2007-04-03 | — | — | US | disclosed |
| US-7199136-B2 | 1,4-dihydro-1,4-diphenylpyridine derivatives | BAYER HEALTHCARE AG (DE) | 2007-04-03 | — | — | US | disclosed |
| EP-1458682-B1 | 1,4-DIHYDRO-1,4-DIPHENYLPYRIDINE DERIVATIVES | BAYER HEALTHCARE AG (DE) | 2006-08-30 | — | — | EP | disclosed |