Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1B | Q00975 | 8/20 | 0.72 |
| ▸ | PPARA | Q07869 | 2/20 | 0.46 |
| ▸ | PPARG | P37231 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.43 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.43 |
| ▸ | KLK7 | P49862 | 1/20 | 0.42 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
| ▸ | CTSL | P07711 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5403965 | 0.88 | CACNA1B (0.73) | CACNA1BPPARAPPARGALDH1A1LMNA | |
| SCHEMBL5351808 | 0.87 | CACNA1B (0.72) | CACNA1BPPARAPPARGALDH1A1LMNA | |
| SCHEMBL5349474 | 0.84 | CACNA1B (1.00) | CACNA1BPPARAPPARGALDH1A1LMNA | |
| SCHEMBL5346162 | 0.84 | CACNA1B (1.00) | CACNA1BPPARAPPARGALDH1A1LMNA | |
| SCHEMBL5350362 | 0.84 | CACNA1B (1.00) | CACNA1BPPARAPPARGALDH1A1LMNA | |
| SCHEMBL5353591 | 0.84 | CACNA1B (1.00) | CACNA1BPPARAPPARGALDH1A1LMNA | |
| SCHEMBL5357001 | 0.83 | CACNA1B (0.98) | CACNA1BPPARAPPARGALDH1A1LMNA | |
| SCHEMBL5347423 | 0.83 | CACNA1B (0.98) | CACNA1BPPARAPPARGALDH1A1LMNA | |
| SCHEMBL5348530 | 0.83 | CACNA1B (0.69) | CACNA1BPPARAPPARGALDH1A1LMNA | |
| SCHEMBL5355682 | 0.82 | CACNA1B (0.70) | CACNA1BPPARAPPARGALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0997147-B1 | AMINO ACID DERIVATIVES | ONO PHARMACEUTICAL CO (JP) | 2006-03-15 | — | — | EP | disclosed |
| EP-0997147-A1 | AMINO ACID DERIVATIVES | Ono Pharmaceutical Co., Ltd. (JP) | 2000-05-03 | — | — | EP | disclosed |