Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 16/20 | 0.66 |
| ▸ | F10 | P00742 | 6/20 | 0.66 |
| ▸ | PRSS1 | P07477 | 11/20 | 0.46 |
| ▸ | FBP1 | P09467 | 4/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL5123592 | 0.94 | F2 (0.60) | F2F10PRSS1FBP1 | |
| SCHEMBL5753161 | 0.93 | F2 (0.64) | F2F10PRSS1FBP1 | |
| SCHEMBL5755835 | 0.91 | F2 (0.78) | F2F10PRSS1FBP1 | |
| Hydrochloric Acid SCHEMBL5851676 | 0.91 | F2 (0.77) | F2F10PRSS1FBP1 | |
| SCHEMBL5754216 | 0.87 | F2 (0.65) | F2F10PRSS1FBP1 | |
| Hydrochloric Acid SCHEMBL5851573 | 0.87 | F2 (0.64) | F2F10PRSS1FBP1 | |
| Trifluoroacetic Acid SCHEMBL5125241 | 0.86 | F2 (0.70) | F2F10PRSS1 | |
| Hydrochloric Acid SCHEMBL5122843 | 0.84 | F2 (0.70) | F2F10PRSS1FBP1 | |
| SCHEMBL5753312 | 0.84 | F2 (0.72) | F2F10PRSS1FBP1 | |
| Trifluoroacetic Acid SCHEMBL5754236 | 0.83 | F2 (0.60) | F2F10PRSS1FBP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1036063-B1 | HETEROARYL AMINOGUANIDINES AND ALKOXYGUANIDINES AND THEIR USE AS PROTEASE INHIBITORS | ORTHO MCNEIL PHARM INC (US) | 2006-11-02 | — | — | EP | claimed |
| US-7402586-B2 | Heteroaryl aminoguanidines and alkoxyguanidines and their use as protease inhibitors | ORTHO-MCNEIL PHARMACEUTICAL, INC. (US) | 2008-07-22 | — | — | US | disclosed |
| US-7402586-B2 | Heteroaryl aminoguanidines and alkoxyguanidines and their use as protease inhibitors | ORTHO-MCNEIL PHARMACEUTICAL, INC. (US) | 2008-07-22 | — | — | US | disclosed |