⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1683966 | 0.64 | — | — | |
| SCHEMBL7559055 | 0.62 | — | — | |
| SCHEMBL11983262 | 0.60 | — | — | |
| SCHEMBL3141020 | 0.56 | — | — | |
| SCHEMBL3375280 | 0.48 | — | — | |
| SCHEMBL8729166 | 0.48 | — | — | |
| SCHEMBL303459 | 0.46 | — | — | |
| SCHEMBL1628866 | 0.44 | — | — | |
| SCHEMBL19168030 | 0.44 | — | — | |
| SCHEMBL358718 | 0.44 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-60199894-A | — | — | None | — | — | JP | disclosed |
| EP-4206184-A1 | PHENOL DERIVATIVE | Sumitomo Pharma Co., Ltd. (JP) | 2023-07-05 | — | — | EP | disclosed |
| WO-2023097031-A1 | BRM TARGETING COMPOUNDS AND ASSOCIATED METHODS OF USE | ARVINAS OPERATIONS, INC. (US) | 2023-06-01 | — | — | WO | disclosed |
| US-20210387967-A1 | 2-HETEROARYL AMINOQUINAZOLINONE DERIVATIVE | SUMITOMO DAINIPPON PHARMA CO., LTD. (JP) | 2021-12-16 | — | — | US | disclosed |
| EP-1446403-B1 | ARYL SUBSTITUTED OXAZOLIDINONES WITH ANTIBACTERIAL ACTIVITY | ASTRAZENECA AB (SE) | 2006-04-12 | — | — | EP | disclosed |
| US-20050043374-A1 | Aryl substituted oxazolidinones with antibacterial activity | ASTRAZENECA AB (SE) | 2005-02-24 | — | — | US | disclosed |
| EP-1446403-A1 | ARYL SUBSTITUTED OXAZOLIDINONES WITH ANTIBACTERIAL ACTIVITY | AstraZeneca AB (SE) | 2004-08-18 | — | — | EP | disclosed |
| WO-2003035648-A1 | ARYL SUBSTITUTED OXAZOLIDINONES WITH ANTIBACTERIAL ACTIVITY | ASTRAZENECA AB (SE) | 2003-05-01 | — | — | WO | disclosed |
| WO-1995016686-A1 | HETEROARYL MUPIROCIN DERIVATIVES USEFUL AS ANTIBACTERIAL, ANTIFUNGAL OR HERBICIDAL AGENTS | SMITHKLINE BEECHAM PLC (GB) | 1995-06-22 | — | — | WO | disclosed |
| EP-0125887-B1 | SYNTHESIS OF THIAZOLES | ELI LILLY AND COMPANY (US) | 1986-12-10 | — | — | EP | disclosed |
| JP-S60199894-A | NOVEL PREPARATION OF CEPHALOSPORIN | TOYAMA CHEM CO LTD | 1985-10-09 | — | — | JP | disclosed |
| EP-0125887-A1 | Synthesis of thiazoles | ELI LILLY AND COMPANY (US) | 1984-11-21 | — | — | EP | disclosed |
| US-4468517-A | Synthesis of thiazoles | ELI LILLY AND COMPANY (US) | 1984-08-28 | — | — | US | disclosed |