Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 7/20 | 0.42 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 5/20 | 0.40 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.39 |
| ▸ | FADS1 | O60427 | 2/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | HTR2B | P41595 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | HTR7 | P34969 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5758163 | 0.86 | SLC2A1 (0.48) | SIGMAR1 | |
| SCHEMBL5756002 | 0.86 | SLC2A1 (0.48) | SIGMAR1 | |
| SCHEMBL5758157 | 0.86 | SLC2A1 (0.48) | SIGMAR1 | |
| SCHEMBL5756495 | 0.83 | SLC2A1 (0.47) | SIGMAR1 | |
| SCHEMBL5756486 | 0.83 | SLC2A1 (0.47) | SIGMAR1 | |
| SCHEMBL5755501 | 0.79 | SLC2A1 (0.48) | SIGMAR1 | |
| SCHEMBL5755499 | 0.79 | SLC2A1 (0.48) | SIGMAR1 | |
| SCHEMBL5755495 | 0.79 | SLC2A1 (0.48) | SIGMAR1 | |
| SCHEMBL5758527 | 0.76 | SLC2A1 (0.47) | SIGMAR1 | |
| SCHEMBL5758524 | 0.76 | SLC2A1 (0.47) | SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1343765-B1 | QUINOLINES AND NITROGENATED DERIVATIVES THEREOF SUBSTITUTED IN 4-POSITION BY A PIPERAZINE-CONTAINING MOIETY AND THEIR USE AS ANTIBACTERIAL AGENTS | SMITHKLINE BEECHAM PLC (GB) | 2006-11-22 | — | — | EP | claimed |