Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 20/20 | 0.42 |
| ▸ | PRSS1 | P07477 | 14/20 | 0.38 |
| ▸ | F10 | P00742 | 3/20 | 0.38 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.37 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL5124174 | 0.95 | F2 (0.40) | F2PRSS1F10PRSS2PRSS3 | |
| SCHEMBL5754902 | 0.91 | F2 (0.41) | F2PRSS1F10PRSS2PRSS3 | |
| SCHEMBL5757032 | 0.89 | F2 (0.40) | F2PRSS1F10PRSS2PRSS3 | |
| SCHEMBL5755510 | 0.89 | F2 (0.44) | F2PRSS1F10PRSS2PRSS3 | |
| SCHEMBL5755463 | 0.88 | S100A9 (0.39) | F2PRSS1PRSS2PRSS3 | |
| SCHEMBL5754864 | 0.88 | F2 (0.49) | F2PRSS1F10PRSS2PRSS3 | |
| SCHEMBL5757591 | 0.87 | F2 (0.49) | F2PRSS1F10PRSS2PRSS3 | |
| Trifluoroacetic Acid SCHEMBL5852595 | 0.86 | F2 (0.39) | F2PRSS1F10PRSS2PRSS3 | |
| SCHEMBL5753969 | 0.85 | F2 (0.50) | F2PRSS1F10PRSS2PRSS3 | |
| Trifluoroacetic Acid SCHEMBL5116083 | 0.85 | F2 (0.40) | F2PRSS1F10PRSS2PRSS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1036063-B1 | HETEROARYL AMINOGUANIDINES AND ALKOXYGUANIDINES AND THEIR USE AS PROTEASE INHIBITORS | ORTHO MCNEIL PHARM INC (US) | 2006-11-02 | — | — | EP | claimed |