Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1B | Q00975 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 2/20 | 0.40 |
| ▸ | DRD3 | P35462 | 2/20 | 0.40 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CTSL | P07711 | 1/20 | 0.36 |
| ▸ | CTSB | P07858 | 1/20 | 0.36 |
| ▸ | CTSS | P25774 | 1/20 | 0.36 |
| ▸ | CTSK | P43235 | 1/20 | 0.36 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.36 |
| ▸ | REN | P00797 | 1/20 | 0.35 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5123449 | 0.91 | CYP2C19 (0.44) | CACNA1BATMHSD17B10L3MBTL1SMN1; SMN2 | |
| SCHEMBL5124110 | 0.91 | CYP2C19 (0.44) | CACNA1BATMHSD17B10L3MBTL1SMN1; SMN2 | |
| SCHEMBL5124757 | 0.91 | CYP2C19 (0.44) | CACNA1BATMHSD17B10L3MBTL1SMN1; SMN2 | |
| SCHEMBL5123437 | 0.91 | CYP2C19 (0.44) | CACNA1BATMHSD17B10L3MBTL1SMN1; SMN2 | |
| SCHEMBL4564775 | 0.91 | CYP2C19 (0.44) | CACNA1BATMHSD17B10L3MBTL1SMN1; SMN2 | |
| Bromide SCHEMBL5123871 | 0.90 | CYP2C19 (0.44) | CACNA1BATMHSD17B10L3MBTL1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL5117576 | 0.90 | CYP2C19 (0.44) | CACNA1BATMHSD17B10L3MBTL1SMN1; SMN2 | |
| SCHEMBL5117048 | 0.90 | CYP2C19 (0.43) | CACNA1BATMHSD17B10SMN1; SMN2MEN1 | |
| Hydrochloric Acid SCHEMBL5125644 | 0.89 | CYP2C19 (0.43) | CACNA1BATMHSD17B10SMN1; SMN2MEN1 | |
| SCHEMBL5754129 | 0.88 | ATM (0.37) | CACNA1BATMHSD17B10L3MBTL1CTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0997147-B1 | AMINO ACID DERIVATIVES | ONO PHARMACEUTICAL CO (JP) | 2006-03-15 | — | — | EP | claimed |
| EP-0997147-A1 | AMINO ACID DERIVATIVES | Ono Pharmaceutical Co., Ltd. (JP) | 2000-05-03 | — | — | EP | claimed |
| EP-0997147-B1 | AMINO ACID DERIVATIVES | ONO PHARMACEUTICAL CO (JP) | 2006-03-15 | — | — | EP | disclosed |
| EP-0997147-A1 | AMINO ACID DERIVATIVES | Ono Pharmaceutical Co., Ltd. (JP) | 2000-05-03 | — | — | EP | disclosed |