Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31028720 | 0.85 | NOTUM (0.74) | NOTUMCYP1A2 | |
| SCHEMBL5541925 | 0.80 | NOTUM (1.00) | NOTUM | |
| SCHEMBL2104782 | 0.78 | NOTUM (0.63) | NOTUMCYP1A2 | |
| SCHEMBL23825594 | 0.77 | NOTUM (0.62) | NOTUMCYP1A2 | |
| SCHEMBL31335420 | 0.77 | NOTUM (0.62) | NOTUMCYP1A2 | |
| SCHEMBL1404525 | 0.77 | NOTUM (0.62) | NOTUMCYP1A2 | |
| SCHEMBL15552224 | 0.77 | NOTUM (0.71) | NOTUMCYP1A2 | |
| Hydrochloric Acid SCHEMBL23826835 | 0.76 | NOTUM (0.60) | NOTUMCYP1A2 | |
| SCHEMBL4720418 | 0.76 | NOTUM (0.60) | NOTUMCYP1A2 | |
| SCHEMBL6127961 | 0.76 | NOTUM (1.00) | NOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0915856-A4 | DIPHENYL HETEROCYCLES AS POTASSIUM CHANNEL MODULATORS | BRISTOL MYERS SQUIBB CO (US) | 2006-04-12 | — | — | EP | disclosed |
| US-6271249-B1 | Diphenyl imidazoles as potassium channel modulators | BRISTOL-MYERS SQUIBB COMPANY | 2001-08-07 | — | — | US | disclosed |
| US-6077861-A | MODULATORS OF THE LARGE-CONDUCTANCE CALCIUM-ACTIVATED POTASSIUM (BK) CHANNELS, THEREFORE, USEFUL IN THE TREATMENT OF ISCHEMIC STROKE | BRISTOL-MYERS SQUIBB COMPANY (US) | 2000-06-20 | — | — | US | disclosed |
| EP-0915856-A1 | DIPHENYL HETEROCYCLES AS POTASSIUM CHANNEL MODULATORS | Bristol-Myers Squibb Company (US) | 1999-05-19 | — | — | EP | disclosed |
| US-5869509-A | TREAT DISORDERS RESPONSIVE TO OPENERS OF THE LARGE CONDUCTANCE CALCIUM-ACTIVATED POTASSIUM CHANNELS | BRISTOL-MYERS SQUIBB COMPANY (US) | 1999-02-09 | — | — | US | disclosed |
| WO-1998004135-A1 | DIPHENYL HETEROCYCLES AS POTASSIUM CHANNEL MODULATORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 1998-02-05 | — | — | WO | disclosed |