Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 2/20 | 0.62 |
| ▸ | ACACB | O00763 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.52 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.52 |
| ▸ | MME | P08473 | 3/20 | 0.51 |
| ▸ | ACE | P12821 | 3/20 | 0.51 |
| ▸ | ACE2 | Q9BYF1 | 3/20 | 0.51 |
| ▸ | CPA1 | P15085 | 2/20 | 0.51 |
| ▸ | CTSS | P25774 | 1/20 | 0.50 |
| ▸ | CTSK | P43235 | 1/20 | 0.50 |
| ▸ | PAM | P19021 | 1/20 | 0.50 |
| ▸ | MMP8 | P22894 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6438662 | 1.00 | TACR1 (0.62) | TACR1ACACBTP53HDAC1HDAC6 | |
| SCHEMBL6438660 | 1.00 | TACR1 (0.62) | TACR1ACACBTP53HDAC1HDAC6 | |
| SCHEMBL242242 | 0.93 | TACR1 (0.71) | TACR1TP53CTSSCTSKPAM | |
| SCHEMBL242241 | 0.93 | TACR1 (0.71) | TACR1TP53CTSSCTSKPAM | |
| Acetic Acid SCHEMBL27445733 | 0.91 | TACR1 (0.69) | TACR1TP53CTSSCTSKPAM | |
| SCHEMBL18733473 | 0.88 | HDAC1 (0.64) | TACR1ACACBHDAC1HDAC6 | |
| SCHEMBL16523532 | 0.88 | HDAC1 (0.64) | TACR1ACACBHDAC1HDAC6 | |
| SCHEMBL25669539 | 0.88 | TACR1 (0.58) | TACR1ACACBTP53MMEACE | |
| SCHEMBL11759813 | 0.87 | TACR1 (0.64) | TACR1TP53HDAC1CTSSCTSK | |
| SCHEMBL11758374 | 0.87 | TACR1 (0.64) | TACR1TP53HDAC1CTSSCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1208092-B1 | SULFONAMIDE DERIVATIVE AS A MATRIX METALLOPROTEINASE INHIBITOR | SAMSUNG ELECTRONICS CO LTD (KR) | 2006-06-21 | — | — | EP | disclosed |