Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 19/20 | 0.51 |
| ▸ | PPARA | Q07869 | 5/20 | 0.41 |
| ▸ | PPARD | Q03181 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5759278 | 0.87 | PPARG (0.63) | PPARGPPARAPPARD | |
| SCHEMBL5761030 | 0.85 | PPARG (0.63) | PPARGPPARAPPARD | |
| SCHEMBL5757439 | 0.85 | PPARG (0.51) | PPARGPPARAPPARD | |
| SCHEMBL5761049 | 0.83 | PPARG (0.51) | PPARGPPARAPPARD | |
| SCHEMBL5757404 | 0.82 | PPARG (0.55) | PPARGPPARAPPARD | |
| SCHEMBL7470392 | 0.82 | PPARG (0.57) | PPARGPPARAPPARD | |
| SCHEMBL5759788 | 0.81 | PPARG (0.61) | PPARGPPARAPPARD | |
| SCHEMBL5206526 | 0.79 | PPARG (0.80) | PPARGPPARAPPARD | |
| SCHEMBL5760312 | 0.79 | PPARG (0.60) | PPARGPPARAPPARD | |
| SCHEMBL5760449 | 0.79 | PPARG (0.54) | PPARGPPARAPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1194146-B1 | ARYLTHIAZOLIDINEDIONE AND ARYLOXAZOLIDINEDIONE DERIVATIVES | MERCK & CO INC (US) | 2006-07-19 | — | — | EP | claimed |