Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 10/20 | 0.38 |
| ▸ | PTGER3 | P43115 | 2/20 | 0.38 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.35 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5763606 | 0.90 | PTGER4 (0.37) | PTGER4CHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL5762200 | 0.84 | PTGER4 (0.39) | PTGER4PTGER3PTGER2CHRM2CHRM4 | |
| SCHEMBL5757165 | 0.84 | PTGER4 (0.51) | PTGER4PTGER3PTGER2 | |
| SCHEMBL5761562 | 0.84 | PTGER4 (0.51) | PTGER4PTGER3PTGER2 | |
| SCHEMBL5762444 | 0.84 | HCRTR1 (0.35) | PTGER4CHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL5508327 | 0.82 | PTGER4 (0.51) | PTGER4 | |
| SCHEMBL14277463 | 0.82 | PTGER4 (0.37) | PTGER4PTGER3PTGER2CHRM2CHRM4 | |
| SCHEMBL5761965 | 0.79 | CAPN1 (0.35) | PTGER4 | |
| SCHEMBL5762382 | 0.79 | HCRTR1 (0.37) | PTGER4CHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL14293926 | 0.79 | PTGER4 (0.44) | PTGER4PTGER3PTGER2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1631355-A1 | PIPERIDINYL PROSTAGLANDIN E ANALOGS | Allergan, Inc. (US) | 2006-03-08 | — | — | EP | disclosed |
| WO-2004108215-A1 | PIPERIDINYL PROSTAGLANDIN E ANALOGS | ALLERGAN, INC. (US) | 2004-12-16 | — | — | WO | disclosed |