Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 20/20 | 0.54 |
| ▸ | SLC6A4 | P31645 | 18/20 | 0.54 |
| ▸ | SLC6A3 | Q01959 | 12/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4488505 | 0.78 | SLC6A2 (0.85) | SLC6A2SLC6A4SLC6A3CYP2D6KCNH2 | |
| SCHEMBL4477264 | 0.78 | SLC6A2 (0.55) | SLC6A2SLC6A4SLC6A3CYP2D6KCNH2 | |
| SCHEMBL4486481 | 0.78 | SLC6A2 (0.86) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL4489204 | 0.77 | SLC6A2 (0.85) | SLC6A2SLC6A4SLC6A3CYP2D6 | |
| SCHEMBL4492096 | 0.77 | SLC6A2 (0.69) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL5793582 | 0.77 | SLC6A2 (0.69) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL4485584 | 0.76 | SLC6A2 (0.65) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL4489401 | 0.75 | SLC6A2 (0.86) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL4493203 | 0.75 | SLC6A2 (0.86) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL4486181 | 0.75 | SLC6A2 (0.86) | SLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1638934-A1 | 3-AMINOPYRROLIDINES AS INHIBITORS OF MONOAMINE UPTAKE | ELI LILLY AND COMPANY (US) | 2006-03-29 | — | — | EP | disclosed |
| WO-2005000811-A1 | 3-AMINOPYRROLIDINES AS INHIBITORS OF MONOAMINE UPTAKE | ELI LILLY AND COMPANY (US) | 2005-01-06 | — | — | WO | disclosed |