Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER1 | P34995 | 1/20 | 0.77 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.77 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.71 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2212907 | 1.00 | PTGER1 (0.77) | PTGER1PTGER3PTGER4PTGER2 | |
| SCHEMBL12288892 | 1.00 | PTGER1 (0.77) | PTGER1PTGER3PTGER4PTGER2 | |
| SCHEMBL4995453 | 0.95 | PTGER1 (0.85) | PTGER1PTGER3PTGER4PTGER2 | |
| SCHEMBL12288895 | 0.89 | PTGER1 (0.63) | PTGER1PTGER3PTGER4PTGER2 | |
| SCHEMBL2210231 | 0.89 | PTGER1 (0.63) | PTGER1PTGER3PTGER4PTGER2 | |
| SCHEMBL4987013 | 0.88 | PTGER1 (0.75) | PTGER1PTGER3PTGER4PTGER2 | |
| SCHEMBL4993351 | 0.88 | PTGER1 (0.75) | PTGER1PTGER3PTGER4PTGER2 | |
| SCHEMBL4992003 | 0.87 | PTGER1 (1.00) | PTGER1PTGER3PTGER4 | |
| SCHEMBL4990731 | 0.87 | PTGER1 (0.74) | PTGER1PTGER3PTGER4 | |
| SCHEMBL4996181 | 0.87 | PTGER3 (0.73) | PTGER1PTGER3PTGER4PTGER2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2006520758-A | — | — | 2006-09-14 | — | — | JP | claimed |
| EP-1613621-A1 | PROSTAGLANDIN ANALOGS AS EP4 RECEPTOR AGONISTS | Merck Frosst Canada Ltd. (CA) | 2006-01-11 | — | — | EP | claimed |
| WO-2004085430-A1 | PROSTAGLANDIN ANALOGS AS EP4 RECEPTOR AGONISTS | MERCK FROSST CANADA LTD. (CA) | 2004-10-07 | — | — | WO | claimed |
| EP-1613621-A1 | PROSTAGLANDIN ANALOGS AS EP4 RECEPTOR AGONISTS | Merck Frosst Canada Ltd. (CA) | 2006-01-11 | — | — | EP | disclosed |
| WO-2004085430-A1 | PROSTAGLANDIN ANALOGS AS EP4 RECEPTOR AGONISTS | MERCK FROSST CANADA LTD. (CA) | 2004-10-07 | — | — | WO | disclosed |