Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERBB2 | P04626 | 5/20 | 0.49 |
| ▸ | MINK1 | Q8N4C8 | 1/20 | 0.49 |
| ▸ | FFAR1 | O14842 | 4/20 | 0.47 |
| ▸ | LCK | P06239 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 6/20 | 0.38 |
| ▸ | PPARA | Q07869 | 6/20 | 0.38 |
| ▸ | RELA | Q04206 | 1/20 | 0.37 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5761665 | 0.88 | ERBB2 (0.49) | ERBB2MINK1FFAR1LCKPPARG | |
| SCHEMBL5761663 | 0.88 | ERBB2 (0.49) | ERBB2MINK1FFAR1LCKPPARG | |
| SCHEMBL5761318 | 0.86 | ERBB2 (0.52) | ERBB2MINK1FFAR1LCKPPARG | |
| SCHEMBL5761322 | 0.86 | ERBB2 (0.52) | ERBB2MINK1FFAR1LCKPPARG | |
| SCHEMBL5760636 | 0.86 | ERBB2 (0.46) | ERBB2MINK1FFAR1LCKPPARG | |
| SCHEMBL5760640 | 0.86 | ERBB2 (0.46) | ERBB2MINK1FFAR1LCKPPARG | |
| SCHEMBL5758035 | 0.85 | ERBB2 (0.54) | ERBB2MINK1FFAR1LCKPPARG | |
| SCHEMBL5758039 | 0.85 | ERBB2 (0.54) | ERBB2MINK1FFAR1LCKPPARG | |
| SCHEMBL5760527 | 0.84 | ERBB2 (0.53) | ERBB2MINK1FFAR1LCKPPARG | |
| SCHEMBL5759709 | 0.84 | ERBB2 (0.53) | ERBB2MINK1FFAR1LCKPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1270571-B1 | Heterocyclic compounds, their production and use | TAKEDA PHARMACEUTICAL (JP) | 2006-09-06 | — | — | EP | disclosed |
| EP-1270571-A1 | Heterocyclic compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2003-01-02 | — | — | EP | disclosed |
| US-6211215-B1 | AROMATIC HETEROCYCLIC COMPOUND WITH AZOLE COMPOUND | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-04-03 | — | — | US | disclosed |