Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 18/20 | 0.37 |
| ▸ | PPARG | P37231 | 13/20 | 0.37 |
| ▸ | PPARD | Q03181 | 10/20 | 0.37 |
| ▸ | PTPRF | P10586 | 1/20 | 0.35 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1749610 | 0.91 | PPARA (0.42) | PPARAPPARGPPARDPTPRFPTPN2 | |
| SCHEMBL1750047 | 0.90 | PPARA (0.42) | PPARAPPARGPPARDPTPRFPTPN2 | |
| SCHEMBL1750048 | 0.90 | PPARA (0.42) | PPARAPPARGPPARDPTPRFPTPN2 | |
| SCHEMBL1750450 | 0.88 | PPARA (0.43) | PPARAPPARGPPARDPTPRFPTPN2 | |
| SCHEMBL1750452 | 0.88 | PPARA (0.43) | PPARAPPARGPPARDPTPRFPTPN2 | |
| SCHEMBL5761770 | 0.86 | PTPRF (0.36) | PPARAPPARGPPARDPTPRFPTPN2 | |
| SCHEMBL5762926 | 0.86 | PPARA (0.40) | PPARAPPARGPPARDPTPRFPTPN2 | |
| SCHEMBL1749558 | 0.84 | PPARA (0.45) | PPARAPPARGPPARD | |
| SCHEMBL1749560 | 0.84 | PPARA (0.45) | PPARAPPARGPPARD | |
| SCHEMBL1749874 | 0.82 | HDAC1 (0.37) | PTPRFPTPN2PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1638964-A1 | NOVEL COMPOUNDS THAT MODULATE PPAR-GAMMA TYPE RECEPTORS, AND USE THEREOF IN COSMETIC OR PHARMACEUTICAL COMPOSITIONS | Galderma Research & Development, S.N.C. (FR) | 2006-03-29 | — | — | EP | disclosed |
| WO-2004113331-A1 | NOVEL COMPOUNDS THAT MODULATE PPARϜ TYPE RECEPTORS, AND USE THEREOF IN COSMETIC OR PHARMACEUTICAL COMPOSITIONS | GALDERMA RESEARCH & DEVELOPMENT, S.N.C. (FR) | 2004-12-29 | — | — | WO | disclosed |