Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 9/20 | 0.46 |
| ▸ | PTGER3 | P43115 | 2/20 | 0.41 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.40 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5757536 | 1.00 | PTGER4 (0.46) | PTGER4PTGER3PTGER2MEN1ALDH1A1 | |
| SCHEMBL5761598 | 0.90 | PTGER4 (0.44) | PTGER4PTGER3PTGER2TSHR | |
| SCHEMBL5502580 | 0.90 | PTGER4 (0.48) | PTGER4 | |
| SCHEMBL5757165 | 0.89 | PTGER4 (0.51) | PTGER4PTGER3PTGER2 | |
| SCHEMBL5761562 | 0.89 | PTGER4 (0.51) | PTGER4PTGER3PTGER2 | |
| SCHEMBL5745965 | 0.89 | PTGER4 (0.42) | PTGER4HCRTR1HCRTR2 | |
| SCHEMBL5761636 | 0.88 | PTGER4 (0.43) | PTGER4PTGER3PTGER2 | |
| SCHEMBL5763606 | 0.85 | PTGER4 (0.37) | PTGER4ALDH1A1KDM4ELMNAHCRTR1 | |
| SCHEMBL4375308 | 0.85 | PTGER4 (0.46) | PTGER4PTGER3PTGER2MEN1ALDH1A1 | |
| SCHEMBL5760085 | 0.85 | PTGER4 (0.46) | PTGER4PTGER3PTGER2MEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1631355-A1 | PIPERIDINYL PROSTAGLANDIN E ANALOGS | Allergan, Inc. (US) | 2006-03-08 | — | — | EP | claimed |
| WO-2004108215-A1 | PIPERIDINYL PROSTAGLANDIN E ANALOGS | ALLERGAN, INC. (US) | 2004-12-16 | — | — | WO | claimed |
| EP-1631355-A1 | PIPERIDINYL PROSTAGLANDIN E ANALOGS | Allergan, Inc. (US) | 2006-03-08 | — | — | EP | disclosed |
| WO-2004108215-A1 | PIPERIDINYL PROSTAGLANDIN E ANALOGS | ALLERGAN, INC. (US) | 2004-12-16 | — | — | WO | disclosed |