Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.37 |
| ▸ | WDR5 | P61964 | 2/20 | 0.37 |
| ▸ | BRS3 | P32247 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | ATP1A1 | P05023 | 2/20 | 0.37 |
| ▸ | ATP1B1 | P05026 | 2/20 | 0.37 |
| ▸ | ATP1A3 | P13637 | 2/20 | 0.37 |
| ▸ | ATP1B2 | P14415 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | ATP4A | P20648 | 2/20 | 0.37 |
| ▸ | ATP1A2 | P50993 | 2/20 | 0.37 |
| ▸ | ATP4B | P51164 | 2/20 | 0.37 |
| ▸ | ATP1B3 | P54709 | 2/20 | 0.37 |
| ▸ | FXYD2 | P54710 | 2/20 | 0.37 |
| ▸ | ATP1A4 | Q13733 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5761022 | 1.00 | CYP2C9 (0.41) | CYP2C9KMT2AALDH1A1HSD17B10WDR5 | |
| SCHEMBL5760989 | 0.99 | CYP2C9 (0.40) | CYP2C9KMT2AALDH1A1HSD17B10WDR5 | |
| SCHEMBL5761001 | 0.95 | CYP2C9 (0.41) | CYP2C9KMT2AALDH1A1HSD17B10WDR5 | |
| SCHEMBL5763843 | 0.94 | CYP2C9 (0.39) | CYP2C9KMT2AALDH1A1HSD17B10WDR5 | |
| SCHEMBL5763970 | 0.94 | CYP2C9 (0.39) | CYP2C9KMT2AALDH1A1HSD17B10WDR5 | |
| SCHEMBL5763833 | 0.94 | CYP2C9 (0.38) | CYP2C9KMT2AALDH1A1HSD17B10WDR5 | |
| SCHEMBL5763949 | 0.93 | CYP2C9 (0.39) | CYP2C9KMT2AALDH1A1HSD17B10WDR5 | |
| SCHEMBL5763839 | 0.89 | CYP2C9 (0.39) | CYP2C9KMT2AALDH1A1HSD17B10WDR5 | |
| SCHEMBL5763690 | 0.89 | CYP2C9 (0.40) | CYP2C9KMT2AALDH1A1HSD17B10WDR5 | |
| SCHEMBL5763954 | 0.89 | CYP2C9 (0.40) | CYP2C9KMT2AALDH1A1HSD17B10WDR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1556371-B1 | BENZIMIDAZOLE DERIVATIVES AND THEIR USE AS PRODRUGS OF PROTON PUMP INHIBITOR | WINSTON PHARMACEUTICALS LLC (US) | 2006-04-19 | — | — | EP | disclosed |