Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 3/20 | 0.37 |
| ▸ | HCRTR1 | O43613 | 3/20 | 0.36 |
| ▸ | HCRTR2 | O43614 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.34 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5762978 | 1.00 | PTGER4 (0.37) | PTGER4HCRTR1HCRTR2LMNAKDM4E | |
| SCHEMBL14277461 | 0.97 | PTGER4 (0.36) | PTGER4HCRTR1HCRTR2LMNAKDM4E | |
| SCHEMBL5762200 | 0.90 | PTGER4 (0.39) | PTGER4CHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL14277463 | 0.87 | PTGER4 (0.37) | PTGER4CHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL4379665 | 0.86 | HCRTR1 (0.35) | PTGER4HCRTR1HCRTR2LMNAKDM4E | |
| SCHEMBL4379670 | 0.86 | HCRTR1 (0.35) | PTGER4HCRTR1HCRTR2LMNAKDM4E | |
| SCHEMBL5763606 | 0.86 | PTGER4 (0.37) | PTGER4HCRTR1HCRTR2LMNAKDM4E | |
| SCHEMBL4375308 | 0.85 | PTGER4 (0.46) | PTGER4LMNAKDM4EALDH1A1 | |
| SCHEMBL5760085 | 0.85 | PTGER4 (0.46) | PTGER4LMNAKDM4EALDH1A1 | |
| SCHEMBL14302056 | 0.83 | PTGER4 (0.44) | PTGER4LMNAKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1631355-A1 | PIPERIDINYL PROSTAGLANDIN E ANALOGS | Allergan, Inc. (US) | 2006-03-08 | — | — | EP | claimed |
| WO-2004108215-A1 | PIPERIDINYL PROSTAGLANDIN E ANALOGS | ALLERGAN, INC. (US) | 2004-12-16 | — | — | WO | claimed |
| EP-1631355-A1 | PIPERIDINYL PROSTAGLANDIN E ANALOGS | Allergan, Inc. (US) | 2006-03-08 | — | — | EP | disclosed |
| WO-2004108215-A1 | PIPERIDINYL PROSTAGLANDIN E ANALOGS | ALLERGAN, INC. (US) | 2004-12-16 | — | — | WO | disclosed |