Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | NRP1 | O14786 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | BCL6 | P41182 | 1/20 | 0.42 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.42 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.42 |
| ▸ | MTOR | P42345 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5762469 | 0.90 | AOC3 (0.45) | AOC3KDM4ETSHRMAPK1NRP1 | |
| SCHEMBL1753405 | 0.86 | KDM4E (0.49) | AOC3KDM4ETSHRMAPK1NRP1 | |
| SCHEMBL2111718 | 0.82 | AOC3 (0.45) | AOC3KDM4ETSHRMAPK1NRP1 | |
| SCHEMBL27658660 | 0.82 | CNR2 (0.46) | AOC3KDM4ETSHRMAPK1NRP1 | |
| SCHEMBL27681014 | 0.80 | POLB (0.48) | AOC3KDM4ETSHRMAPK1PIK3R1 | |
| SCHEMBL27680984 | 0.73 | POLB (0.48) | KDM4ETSHRMAPK1BCL6CNR2 | |
| SCHEMBL1310155 | 0.70 | PIK3CA (0.65) | PIK3R1PIK3CAMTOR | |
| SCHEMBL1690287 | 0.69 | PTGDR2 (0.56) | AOC3KDM4ECNR2RAB9APOLB | |
| SCHEMBL30540190 | 0.69 | TSHR (0.51) | KDM4ETSHRMAPK1CNR2CYP1A2 | |
| SCHEMBL26635221 | 0.69 | TSHR (0.51) | KDM4ETSHRMAPK1CNR2CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1611091-B1 | Substituted phenylalkanoic acid derivatives and their use for respiratory disease treatment | ASTRAZENECA AB (SE) | 2014-10-29 | — | — | EP | disclosed |
| EP-1611091-A1 | NOVEL COMPOUNDS | AstraZeneca AB (SE) | 2006-01-04 | — | — | EP | disclosed |
| WO-2004089885-A1 | NOVEL COMPOUNDS | ASTRAZENECA AB (SE) | 2004-10-21 | — | — | WO | disclosed |