Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 16/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1753343 | 0.86 | PTGDR2 (0.64) | PTGDR2TDP1TSHRMAPT | |
| SCHEMBL5762743 | 0.84 | PTGDR2 (0.56) | PTGDR2TDP1TSHR | |
| SCHEMBL1690231 | 0.81 | PTGDR2 (0.57) | PTGDR2TDP1TSHR | |
| SCHEMBL1690265 | 0.78 | PTGDR2 (0.68) | PTGDR2TDP1TSHRMAPT | |
| SCHEMBL1753408 | 0.77 | PTGDR2 (0.64) | PTGDR2TDP1TSHRMAPT | |
| SCHEMBL1753770 | 0.76 | PTGDR2 (0.70) | PTGDR2TDP1TSHRMAPT | |
| SCHEMBL1690311 | 0.76 | PTGDR2 (0.59) | PTGDR2TDP1TSHR | |
| SCHEMBL1753571 | 0.74 | PTGDR2 (0.57) | PTGDR2TDP1 | |
| SCHEMBL2102248 | 0.74 | PTGDR2 (0.60) | PTGDR2TDP1TSHRMAPT | |
| SCHEMBL5173326 | 0.74 | PTGDR2 (0.60) | PTGDR2TDP1TSHRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1611091-A1 | NOVEL COMPOUNDS | AstraZeneca AB (SE) | 2006-01-04 | — | — | EP | disclosed |
| WO-2004089885-A1 | NOVEL COMPOUNDS | ASTRAZENECA AB (SE) | 2004-10-21 | — | — | WO | disclosed |