SCHEMBL5763192

SCHEMBL5763192

NC1CCN(CC(c2cccc(Cl)c2)C2(O)CCCCC2)C1

nearest known ligand 0.66

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
SLC6A2 P23975 20/20 0.66
SLC6A3 Q01959 13/20 0.66
SLC6A4 P31645 11/20 0.66

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3986831 1.00 SLC6A2 (0.66) SLC6A2SLC6A3SLC6A4
SCHEMBL3959547 1.00 SLC6A2 (0.66) SLC6A2SLC6A3SLC6A4
SCHEMBL3992609 1.00 SLC6A2 (0.66) SLC6A2SLC6A3SLC6A4
SCHEMBL3951816 1.00 SLC6A2 (0.66) SLC6A2SLC6A3SLC6A4
Hydrochloric Acid SCHEMBL3952536 0.99 SLC6A2 (0.67) SLC6A2SLC6A3SLC6A4
Hydrochloric Acid SCHEMBL3956450 0.99 SLC6A2 (0.67) SLC6A2SLC6A3SLC6A4
Hydrochloric Acid SCHEMBL6371688 0.99 SLC6A2 (0.67) SLC6A2SLC6A3SLC6A4
Hydrochloric Acid SCHEMBL3956710 0.99 SLC6A2 (0.67) SLC6A2SLC6A3SLC6A4
Hydrochloric Acid SCHEMBL3956074 0.99 SLC6A2 (0.67) SLC6A2SLC6A3SLC6A4
SCHEMBL3960407 0.93 SLC6A2 (0.72) SLC6A2SLC6A3SLC6A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1673084-A1 1-2' (1,4'-BIPERIDIN-1'-YL)-1-(PHENYL)-ETHYLCYCLOHEXANOL DERIVATIVES AS MONOAMINE REUPTAKE MODULATORS FOR THE TREATMENT OF VASOMOTOR SYMPTOMS Wyeth (US) 2006-06-28 EP disclosed
WO-2005037279-A1 1- 2’ (1, 4’-BIPERIDIN-1’-YL)-1- (PHENYL) -ETHYL CYCLOHEXANOL DERIVATIVES AS MONOAMINE REUPTAKE MODULATORS FOR THE TREATMENT OF VISOMOTOR SYMPTOMS WYETH (US) 2005-04-28 WO disclosed