Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 17/20 | 0.47 |
| ▸ | PPARA | Q07869 | 14/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | PPARD | Q03181 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.39 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1750740 | 0.91 | PPARG (0.48) | PPARGPPARAFFAR1PPARD | |
| SCHEMBL1749436 | 0.90 | PPARG (0.48) | PPARGPPARAFFAR1PPARD | |
| SCHEMBL1749665 | 0.81 | PPARA (0.41) | PPARGPPARAPPARDNPC1NFKB1 | |
| SCHEMBL5760267 | 0.81 | PPARG (0.47) | PPARGPPARAFFAR1PPARD | |
| SCHEMBL1749906 | 0.80 | PPARA (0.40) | PPARGPPARAPPARDNPC1NFKB1 | |
| SCHEMBL5761436 | 0.80 | PPARG (0.46) | PPARGPPARAFFAR1PPARD | |
| SCHEMBL5567583 | 0.78 | AOC3 (0.47) | PPARGPPARAPPARD | |
| SCHEMBL6184829 | 0.78 | AOC3 (0.47) | PPARGPPARAPPARD | |
| SCHEMBL1750943 | 0.77 | PPARA (0.42) | PPARGPPARAPPARDNPC1RAB9A | |
| SCHEMBL1749462 | 0.76 | PPARA (0.42) | PPARGPPARAPPARDNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1638964-A1 | NOVEL COMPOUNDS THAT MODULATE PPAR-GAMMA TYPE RECEPTORS, AND USE THEREOF IN COSMETIC OR PHARMACEUTICAL COMPOSITIONS | Galderma Research & Development, S.N.C. (FR) | 2006-03-29 | — | — | EP | claimed |
| WO-2004113331-A1 | NOVEL COMPOUNDS THAT MODULATE PPARϜ TYPE RECEPTORS, AND USE THEREOF IN COSMETIC OR PHARMACEUTICAL COMPOSITIONS | GALDERMA RESEARCH & DEVELOPMENT, S.N.C. (FR) | 2004-12-29 | — | — | WO | claimed |