Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK11 | Q15759 | 5/20 | 0.55 |
| ▸ | MAPK14 | Q16539 | 5/20 | 0.55 |
| ▸ | MAPK13 | O15264 | 2/20 | 0.35 |
| ▸ | RAF1 | P04049 | 2/20 | 0.35 |
| ▸ | MAPK12 | P53778 | 2/20 | 0.35 |
| ▸ | KIF11 | P52732 | 1/20 | 0.32 |
| ▸ | F2R | P25116 | 2/20 | 0.30 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6220074 | 0.92 | MAPK11 (0.56) | MAPK11MAPK14RAF1 | |
| SCHEMBL6220174 | 0.91 | MAPK14 (0.48) | MAPK11MAPK14MAPK13RAF1MAPK12 | |
| SCHEMBL5764109 | 0.91 | MAPK14 (0.48) | MAPK11MAPK14MAPK13RAF1MAPK12 | |
| SCHEMBL5764416 | 0.91 | MAPK14 (0.67) | MAPK11MAPK14 | |
| SCHEMBL5763394 | 0.91 | MAPK14 (0.67) | MAPK11MAPK14 | |
| SCHEMBL6218157 | 0.91 | MAPK14 (0.67) | MAPK11MAPK14 | |
| SCHEMBL5764180 | 0.89 | MAPK14 (0.55) | MAPK11MAPK14MAPK13RAF1MAPK12 | |
| SCHEMBL5763263 | 0.89 | MAPK11 (0.48) | MAPK11MAPK14 | |
| SCHEMBL6222012 | 0.88 | MAPK14 (0.65) | MAPK11MAPK14MAPK13MAPK12 | |
| SCHEMBL6219480 | 0.87 | MAPK11 (0.54) | MAPK11MAPK14MAPK13MAPK12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1377577-B1 | PYRROLE DERIVATES FOR TREATING CYTOKINE MEDIATED DISEASES | SANKYO CO (JP) | 2006-06-14 | — | — | EP | claimed |