SCHEMBL57641

SCHEMBL57641

COc1[c]c(OC)ccc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.41
SMN1; SMN2 Q16637 2/20 0.41
KDM4E B2RXH2 2/20 0.41
MAPK1 P28482 2/20 0.41
CA1 P00915 7/20 0.38
CA2 P00918 7/20 0.38
CA7 P43166 5/20 0.38
CA9 Q16790 5/20 0.38
CA12 O43570 3/20 0.38
CA14 Q9ULX7 3/20 0.38
CA4 P22748 2/20 0.38
CYP3A4 P08684 3/20 0.35
TP53 P04637 2/20 0.35
LMNA P02545 1/20 0.35
MAPT P10636 1/20 0.35
HPGD P15428 1/20 0.35
ALOX15 P16050 1/20 0.35
ALOX12 P18054 1/20 0.35
HSD17B10 Q99714 1/20 0.35
ACHE P22303 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29160711 0.89 SMN1; SMN2 (0.35) ALDH1A1SMN1; SMN2KDM4EMAPK1CA1
SCHEMBL29242332 0.85 SMN1; SMN2 (0.34) ALDH1A1SMN1; SMN2KDM4EMAPK1
SCHEMBL455316 0.84
SCHEMBL743598 0.83 SMN1; SMN2 (0.38) ALDH1A1SMN1; SMN2KDM4EMAPK1CYP3A4
SCHEMBL159441 0.83 NPSR1 (0.33) ALDH1A1SMN1; SMN2KDM4EMAPK1
SCHEMBL1068597 0.82
SCHEMBL7496964 0.82
SCHEMBL1028797 0.82
SCHEMBL3297490 0.82
SCHEMBL160707 0.82

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 6111 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12043688-B2 Nickel catalysts with two alkali ions for homopolymerization and copolymerization UNIVERSITY OF HOUSTON SYSTEM (US) 2024-07-23 US claimed
US-12043689-B2 Nickel catalysts with single metal cations for homopolymerization and copolymerization UNIVERSITY OF HOUSTON SYSTEM (US) 2024-07-23 US claimed
CN-118344695-A Hydroxyl-enriched cycloolefin copolymer long afterglow material and application thereof 重庆理工大学 2024-07-16 CN claimed
CN-116332908-B SHP2 allosteric inhibitor and preparation method and application thereof 杭州医学院 2024-07-02 CN claimed
US-20240174603-A1 MODULATORS OF PROTEIN PHOSPHATASE 2A (PP2A) AND METHODS USING SAME RAPPTA THERAPEUTICS OY (FI) 2024-05-30 US claimed
CN-112673012-B Multifunctional bisacylphosphine oxide photoinitiator 意大利艾坚蒙树脂有限公司 2024-05-24 CN claimed
US-20240166775-A1 NICKEL CATALYSTS WITH TWO METAL CATIONS FOR HOMOPOLYMERIZATION AND COPOLYMERIZATION UNIVERSITY OF HOUSTON SYSTEM (US) 2024-05-23 US claimed
CN-118006729-A Reagent combination for detecting sample by immunofluorescence combined fluorescence in situ hybridization technology and application thereof 珠海圣美生物诊断技术有限公司 2024-05-10 CN claimed
CN-117983302-A Catalyst containing ferrocene PNP ligand for ethylene selective tetramerization and preparation method and application thereof 华东理工大学 2024-05-07 CN claimed
US-20240117076-A1 NICKEL CATALYSTS WITH SINGLE METAL CATIONS FOR HOMOPOLYMERIZATION AND COPOLYMERIZATION UNIVERSITY OF HOUSTON SYSTEM (US) 2024-04-11 US claimed
EP-0031080-A1 2-Acylaminomethyl-1,4-benzodiazepines and their salts, as well as a process for their preparation and pharmaceutical compositions containing these compounds Kali-Chemie Pharma GmbH (DE) 1981-07-01 EP claimed
EP-0028497-A1 Beta-lactam antibiotics, their preparation and their use in pharmaceutical compositions BEECHAM GROUP PLC (GB) 1981-05-13 EP claimed
US-4258040-A Cephalosporin compounds MERCK & CO., INC. (US) 1981-03-24 US claimed
US-4252808-A β-Lactam antibacterial agents, their use in pharmaceutical compositions, the process for their preparation and intermediates for use in that process BEECHAM GROUP LIMITED (GB) 1981-02-24 US claimed
EP-0007508-A2 Acylphosphinoxide compounds, their preparation and their use BASF Aktiengesellschaft (DE) 1980-02-06 EP claimed
EP-0000891-B1 SYNERGISTIC COMBINATIONS OF PENICILLINS AND ANTIBIOTIC AGENTS CONTAINING THEM BAYER AG (DE) 1980-01-09 EP claimed
EP-0004134-A1 Beta-lactam antibacterial agents, their pharmaceutical compositions and process for their preparation BEECHAM GROUP PLC (GB) 1979-09-19 EP claimed
US-4118232-A Photographic material containing sulphonic acid group containing disazo dyestuffs CIBA-GEIGY AG (CH) 1978-10-03 US claimed
US-4060687-A Cephalosporins having a 3-α substituted alkyl grouping MERCK & CO., INC. (US) 1977-11-29 US claimed
US-3979508-A PENICILLOYL-POLYLYSINE KREMERS-URBAN COMPANY (US) 1976-09-07 US claimed