Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 18/20 | 0.42 |
| ▸ | FLT1 | P17948 | 1/20 | 0.35 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.35 |
| ▸ | MINK1 | Q8N4C8 | 1/20 | 0.35 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4079695 | 0.81 | MAPK14 (0.46) | MAPK14 | |
| SCHEMBL5765801 | 0.80 | MAPK14 (0.39) | MAPK14 | |
| SCHEMBL5766672 | 0.80 | MAPK14 (0.51) | MAPK14FLT1MAPK11MINK1 | |
| SCHEMBL10364829 | 0.78 | FLT1 (0.46) | MAPK14FLT1MAPK11MINK1 | |
| SCHEMBL4132478 | 0.76 | MAPK14 (0.43) | MAPK14FLT1MAPK11MINK1 | |
| SCHEMBL4130612 | 0.76 | FLT1 (0.43) | MAPK14FLT1MAPK11MINK1 | |
| SCHEMBL5766104 | 0.76 | MAPK14 (0.56) | MAPK14FLT1MAPK11MINK1APOBEC3G | |
| SCHEMBL4825090 | 0.76 | MAPK14 (0.67) | MAPK14APOBEC3G | |
| SCHEMBL15086682 | 0.76 | FLT1 (0.42) | MAPK14FLT1MAPK11MINK1 | |
| SCHEMBL4079593 | 0.75 | MAPK14 (0.40) | MAPK14FLT1MAPK11MINK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1601672-B1 | TRIAZOLO-PYRIDINES AS ANTI-INFLAMMATORY COMPOUNDS | PFIZER PROD INC (US) | 2006-07-26 | — | — | EP | disclosed |