SCHEMBL57647

SCHEMBL57647

C[C](C)CC#N

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL67703 0.77
SCHEMBL11895365 0.77 MCL1 (0.41)
SCHEMBL2473688 0.77 MCL1 (0.41)
SCHEMBL11405904 0.72
SCHEMBL3584559 0.72
SCHEMBL86002 0.72
SCHEMBL970371 0.72
SCHEMBL16532961 0.72
SCHEMBL7846909 0.72
SCHEMBL5374345 0.70

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2071 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117529485-A Novel compound and organic light emitting device comprising the same 株式会社LG化学 2024-02-06 CN claimed
US-20230399297-A1 Novel Glutamine Analogs JACOBIO PHARMACEUTICALS CO., LTD (CN) 2023-12-14 US claimed
CN-116916963-A Multivalent ligand clusters with diamine scaffolds for targeted delivery of therapeutic agents 上海舶望制药有限公司 2023-10-20 CN claimed
WO-2023159155-A1 INHIBITORS OF PHOSPHOINOSITIDE 3-KINASE (PI3K) AND USES THEREOF PIVALENT THERAPEUTICS, INC. (US) 2023-08-24 WO claimed
WO-2023068824-A1 NOVEL COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING SAME 주식회사 엘지화학 2023-04-27 WO claimed
CN-114206389-A Multivalent ligand clusters for targeted delivery of therapeutic agents 有丝分裂疗法有限责任公司 2022-03-18 CN claimed
EP-3923989-A1 MULTIVALENT LIGAND CLUSTERS FOR TARGETED DELIVERY OF THERAPEUTIC AGENTS Mitotherapeutix LLC (US) 2021-12-22 EP claimed
EP-3897644-A1 COMPOUNDS THAT PARTICIPATE IN COOPERATIVE BINDING AND USES THEREOF Revolution Medicines, Inc. (US) 2021-10-27 EP claimed
CN-113498342-A Compounds involved in synergistic binding and uses thereof 锐新医药公司 2021-10-12 CN claimed
CN-113474352-A Novel phosphoramidites 罗氏创新中心哥本哈根有限公司 2021-10-01 CN claimed
US-20050048601-A1 Method for polynucleotide synthesis REGENTS OF THE UNIVERSITY OF COLORADO, THE 2005-03-03 US claimed
EP-1510523-A1 Precurors for two-step polynucleotide synthesis Agilent Technologies Inc (US) 2005-03-02 EP claimed
US-20040116687-A1 oligonucleotides having reduced internucleotide charge and enhanced nuclease resistance AGILENT TECHNOLOGIES, INC. 2004-06-17 US claimed
US-6630581-B2 Condensing the 3'-OH or 5'-OH group of a support-bound nucleoside or oligonucleotide with a monomeric nucleoside phosphoramidite having a carbonate-protected hydroxyl group; treating the intermediate provided with a deprotecting reagent AGILENT TECHNOLOGIES, INC. 2003-10-07 US claimed
EP-1334111-A2 PHOSPHINOAMIDITE CARBOXYLATES AND ANALOGS THEREOF IN THE SYNTHESIS OF OLIGONUCLEOTIDES HAVING REDUCED INTERNUCLEOTIDE CHARGE Dellinger, Douglas J. (US) 2003-08-13 EP claimed
WO-2002032912-A2 PHOSPHINOAMIDITE CARBOXYLATES AND ANALOGS THEREOF IN THE SYNTHESIS OF OLIGONUCLEOTIDES HAVING REDUCED INTERNUCLEOTIDE CHARGE DELLINGER DOUGLAS J (US) 2002-04-25 WO claimed
US-6153742-A SOLID PHASE SYNTHESIS PRODUCING ANTISENSE OLIGONUCLEOTIDES UNIVERSITY OF BARCELONA (ES) 2000-11-28 US claimed
US-5837873-A PROTECTED OXYDIAMINES ABBOTT LABORATORIES (US) 1998-11-17 US claimed
US-4898939-A Process for preparing 2β-substituted-methylpenicillin derivatives TAIHO PHARMACEUTICAL CO., LTD. (JP) 1990-02-06 US claimed
US-4665067-A BACTERICIDES TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1987-05-12 US claimed