Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 20/20 | 0.73 |
| ▸ | ADORA3 | P0DMS8 | 5/20 | 0.71 |
| ▸ | ADORA2B | P29275 | 5/20 | 0.71 |
| ▸ | ADORA1 | P30542 | 5/20 | 0.71 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5764746 | 1.00 | ADORA2A (0.73) | ADORA2AADORA3ADORA2BADORA1 | |
| SCHEMBL5762878 | 1.00 | ADORA2A (0.73) | ADORA2AADORA3ADORA2BADORA1 | |
| SCHEMBL5763570 | 0.94 | ADORA2A (0.75) | ADORA2AADORA3ADORA2BADORA1 | |
| SCHEMBL5764520 | 0.94 | ADORA2A (0.75) | ADORA2AADORA3ADORA2BADORA1 | |
| SCHEMBL6329934 | 0.94 | ADORA2A (0.75) | ADORA2AADORA3ADORA2BADORA1 | |
| SCHEMBL5764526 | 0.94 | ADORA2A (0.75) | ADORA2AADORA3ADORA2BADORA1 | |
| SCHEMBL5762287 | 0.92 | ADORA2A (0.72) | ADORA2AADORA3ADORA2BADORA1 | |
| SCHEMBL5765248 | 0.92 | ADORA2A (0.72) | ADORA2AADORA3ADORA2BADORA1 | |
| SCHEMBL5764454 | 0.92 | ADORA2A (0.72) | ADORA2AADORA3ADORA2BADORA1 | |
| SCHEMBL5765253 | 0.92 | ADORA2A (0.72) | ADORA2AADORA3ADORA2BADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1220862-B1 | PURINE DERIVATIVES | PFIZER LTD (GB) | 2006-03-22 | — | — | EP | claimed |