Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 14/20 | 0.60 |
| ▸ | MAOA | P21397 | 7/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.60 |
| ▸ | CALML3 | P27482 | 1/20 | 0.60 |
| ▸ | SDHA | P31040 | 1/20 | 0.60 |
| ▸ | F10 | P00742 | 3/20 | 0.53 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.44 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18709198 | 0.88 | MAOB (0.60) | MAOBMAOALMNAPTGS1CALML3 | |
| SCHEMBL28837347 | 0.85 | MAOB (0.60) | MAOBMAOALMNAPTGS1CALML3 | |
| SCHEMBL27602087 | 0.84 | MAOB (0.58) | MAOBMAOALMNAPTGS1CALML3 | |
| SCHEMBL10038893 | 0.83 | MAOB (0.62) | MAOBMAOALMNAPTGS1CALML3 | |
| SCHEMBL17026089 | 0.83 | MAOB (0.69) | MAOBMAOALMNAPTGS1CALML3 | |
| SCHEMBL12478380 | 0.83 | MAOB (0.69) | MAOBMAOALMNAPTGS1CALML3 | |
| SCHEMBL12006681 | 0.83 | MAOB (0.62) | MAOBMAOALMNAPTGS1CALML3 | |
| SCHEMBL10038450 | 0.83 | MAOB (0.69) | MAOBMAOALMNAPTGS1CALML3 | |
| SCHEMBL17026087 | 0.83 | MAOB (0.62) | MAOBMAOALMNAPTGS1CALML3 | |
| SCHEMBL12478379 | 0.83 | MAOB (0.62) | MAOBMAOALMNAPTGS1CALML3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105111160-B | Linezolid preparation method | 浙江新东港药业股份有限公司 | 2017-04-12 | — | — | CN | disclosed |
| CN-105111160-A | Linezolid preparation method | ZHEJIANG NEO DANKONG PHARMACEUTICAL CO LTD | 2015-12-02 | — | — | CN | disclosed |
| WO-2007138381-A2 | PHOSPHONATED OXAZOLIDINONES AND USES THEREOF FOR THE PREVENTION AND TREATMENT OF BONE AND JOINT INFECTIONS | TARGANTA THERAPEUTICS INC. (CA) | 2007-12-06 | — | — | WO | disclosed |
| EP-1478629-B1 | N-ARYL-2-OXAZOLIDINONE-5-CARBOXAMIDES AND THEIR DERIVATIVES AND THEIR USE AS ANTIBACTERIALS | PHARMACIA & UPJOHN CO LLC (US) | 2006-10-11 | — | — | EP | disclosed |