Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 20/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4860225 | 0.90 | MAPK14 (0.72) | MAPK14 | |
| SCHEMBL5766076 | 0.81 | MAPK14 (0.60) | MAPK14 | |
| SCHEMBL5793153 | 0.80 | MAPK14 (0.59) | MAPK14 | |
| SCHEMBL5765247 | 0.80 | MAPK14 (0.73) | MAPK14 | |
| SCHEMBL5767610 | 0.79 | MAPK14 (0.70) | MAPK14 | |
| SCHEMBL5766994 | 0.79 | MAPK14 (0.67) | MAPK14 | |
| SCHEMBL4820818 | 0.79 | MAPK14 (0.58) | MAPK14 | |
| SCHEMBL5793387 | 0.78 | MAPK14 (0.64) | MAPK14 | |
| SCHEMBL5764175 | 0.78 | MAPK14 (0.57) | MAPK14 | |
| SCHEMBL4823102 | 0.77 | MAPK14 (0.59) | MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7321040-B2 | Triazolo-pyridines as anti-inflammatory compounds | PFIZER INC. (US) | 2008-01-22 | — | — | US | disclosed |
| US-7321040-B2 | Triazolo-pyridines as anti-inflammatory compounds | PFIZER INC. (US) | 2008-01-22 | — | — | US | disclosed |
| EP-1601672-B1 | TRIAZOLO-PYRIDINES AS ANTI-INFLAMMATORY COMPOUNDS | PFIZER PROD INC (US) | 2006-07-26 | — | — | EP | disclosed |