Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK13 | O15264 | 8/20 | 0.67 |
| ▸ | MAPK12 | P53778 | 8/20 | 0.67 |
| ▸ | MAPK11 | Q15759 | 8/20 | 0.67 |
| ▸ | MAPK14 | Q16539 | 8/20 | 0.67 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.49 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.49 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.49 |
| ▸ | FLT4 | P35916 | 1/20 | 0.49 |
| ▸ | KDR | P35968 | 1/20 | 0.49 |
| ▸ | MATK | P42679 | 1/20 | 0.49 |
| ▸ | FRK | P42685 | 1/20 | 0.49 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.49 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.49 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.49 |
| ▸ | CLK2 | P49760 | 1/20 | 0.49 |
| ▸ | GSK3A | P49840 | 1/20 | 0.49 |
| ▸ | GSK3B | P49841 | 1/20 | 0.49 |
| ▸ | CSNK1G2 | P78368 | 1/20 | 0.49 |
| ▸ | TAOK1 | Q7L7X3 | 1/20 | 0.49 |
| ▸ | MINK1 | Q8N4C8 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5772264 | 0.95 | MAPK13 (0.72) | MAPK13MAPK12MAPK11MAPK14DYRK3 | |
| SCHEMBL5771099 | 0.90 | MAPK14 (0.61) | MAPK13MAPK12MAPK11MAPK14 | |
| SCHEMBL5766540 | 0.90 | MAPK14 (0.65) | MAPK13MAPK12MAPK11MAPK14DYRK3 | |
| SCHEMBL5772018 | 0.90 | MAPK13 (0.74) | MAPK13MAPK12MAPK11MAPK14DYRK3 | |
| SCHEMBL5771822 | 0.88 | MAPK14 (0.55) | MAPK13MAPK12MAPK11MAPK14 | |
| SCHEMBL5770307 | 0.88 | MAPK14 (0.57) | MAPK13MAPK12MAPK11MAPK14 | |
| SCHEMBL5770434 | 0.88 | MAPK14 (0.66) | MAPK13MAPK12MAPK11MAPK14DYRK3 | |
| SCHEMBL5769717 | 0.88 | MAPK13 (0.72) | MAPK13MAPK12MAPK11MAPK14DYRK3 | |
| SCHEMBL5771731 | 0.88 | MAPK13 (0.58) | MAPK13MAPK12MAPK11MAPK14 | |
| SCHEMBL5771553 | 0.87 | MAPK13 (0.70) | MAPK13MAPK12MAPK11MAPK14DYRK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0988301-B1 | IMIDAZOLYL-CYCLIC ACETALS | AVENTIS PHARMA LTD (GB) | 2006-08-09 | — | — | EP | disclosed |
| US-6989395-B2 | Imidazolyl-cyclic acetals | AVENTIS PHARMA LIMITED (GB) | 2006-01-24 | — | — | US | disclosed |
| US-20040038991-A1 | Imidazolyl-cyclic acetals | AVENTIS PHARMA LIMITED (GB) | 2004-02-26 | — | — | US | disclosed |
| US-6602877-B1 | Imidazolyl-cyclic acetals | AVENTIS PHARMA LIMITED (GB) | 2003-08-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040038991-A1 | Imidazolyl-cyclic acetals | CBR1, LBR, CBR3 | MAPK13 1610/4885MAPK12 2766/4885MAPK11 1125/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.