Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 11/20 | 0.55 |
| ▸ | MAPK13 | O15264 | 7/20 | 0.55 |
| ▸ | MAPK12 | P53778 | 7/20 | 0.55 |
| ▸ | MAPK11 | Q15759 | 7/20 | 0.55 |
| ▸ | GSK3B | P49841 | 2/20 | 0.38 |
| ▸ | KCNH3 | Q9ULD8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7217798 | 0.79 | MAPK14 (0.48) | MAPK14MAPK13MAPK12MAPK11 | |
| SCHEMBL6075400 | 0.79 | MAPK14 (0.80) | MAPK14MAPK13MAPK12MAPK11 | |
| SCHEMBL6809563 | 0.77 | MAPK14 (0.69) | MAPK14MAPK13MAPK12MAPK11GSK3B | |
| SCHEMBL6075673 | 0.76 | MAPK14 (0.47) | MAPK14MAPK13MAPK12MAPK11 | |
| SCHEMBL5769609 | 0.75 | MAPK14 (0.82) | MAPK14MAPK13MAPK12MAPK11 | |
| SCHEMBL6808788 | 0.75 | MAPK14 (0.56) | MAPK14MAPK13MAPK12MAPK11GSK3B | |
| SCHEMBL5773002 | 0.75 | MAPK14 (0.55) | MAPK14MAPK13MAPK12MAPK11 | |
| SCHEMBL5773346 | 0.75 | MAPK14 (0.55) | MAPK14MAPK13MAPK12MAPK11 | |
| SCHEMBL5770008 | 0.74 | MAPK14 (0.85) | MAPK14MAPK13MAPK12MAPK11 | |
| SCHEMBL5769916 | 0.73 | MAPK14 (0.81) | MAPK14MAPK13MAPK12MAPK11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0988301-B1 | IMIDAZOLYL-CYCLIC ACETALS | AVENTIS PHARMA LTD (GB) | 2006-08-09 | — | — | EP | disclosed |