Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A2 | P19784 | 10/20 | 0.53 |
| ▸ | CSNK2A1 | P68400 | 10/20 | 0.53 |
| ▸ | PTGER1 | P34995 | 6/20 | 0.45 |
| ▸ | PTGER4 | P35408 | 4/20 | 0.45 |
| ▸ | PTGER3 | P43115 | 4/20 | 0.45 |
| ▸ | PTGER2 | P43116 | 4/20 | 0.45 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.44 |
| ▸ | CDK2 | P24941 | 2/20 | 0.44 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.44 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | BRD4 | O60885 | 1/20 | 0.42 |
| ▸ | GLS | O94925 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1715500 | 0.81 | PTGER1 (0.43) | PTGER1PTGER4PTGER3PTGER2CCNE1 | |
| SCHEMBL1260011 | 0.80 | MAPK1 (0.42) | CSNK2A2CSNK2A1CCNE1CDK2CDK5 | |
| SCHEMBL28014843 | 0.79 | KDR (0.62) | CSNK2A2CSNK2A1CCNE1CDK2CDK5 | |
| SCHEMBL2953087 | 0.79 | GAA (0.41) | PTGER1PTGER4PTGER3PTGER2CYP2C9 | |
| SCHEMBL8282581 | 0.79 | PTGER1 (0.40) | PTGER1PTGER4PTGER3PTGER2CCNE1 | |
| SCHEMBL12462645 | 0.78 | PTPN1 (0.42) | PTGER1PTGER4PTGER3PTGER2CYP2C9 | |
| SCHEMBL1716179 | 0.78 | LIMK1 (0.41) | CSNK2A2CSNK2A1CCNE1CDK2CDK5 | |
| SCHEMBL1260986 | 0.76 | CSNK2A2 (0.47) | CSNK2A2CSNK2A1CCNE1CDK2CDK5 | |
| SCHEMBL8283417 | 0.76 | PTGER1 (0.38) | PTGER1PTGER4PTGER3PTGER2CCNE1 | |
| SCHEMBL12027281 | 0.76 | CCNE1 (0.51) | CCNE1CDK2CDK5CCNE2GLS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1709018-A1 | ACYLAMINOTHIAZOLE DERIVATIVES AND USE THEREOF AS BETA-AMYLOID INHIBITORS | Sanofi-Aventis (FR) | 2006-10-11 | — | — | EP | disclosed |
| WO-2005073202-A1 | ACYLAMINOTHIAZOLE DERIVATIVES AND USE THEREOF AS BETA-AMYLOID INHIBITORS | SANOFI-AVENTIS (FR) | 2005-08-11 | — | — | WO | disclosed |