SCHEMBL5768089

SCHEMBL5768089

CN(C)CCN(C)C(=O)CN(C1CCCN(c2ccc(-c3ccccc3)c(S(C)(=O)=O)c2F)C1=O)S(=O)(=O)c1ccc2cc(Cl)ccc2c1

nearest known ligand 0.69

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
F10 P00742 20/20 0.69

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5914269 0.91 F10 (0.73) F10
SCHEMBL4680653 0.85 F10 (0.83) F10
SCHEMBL6988052 0.83 F10 (0.58) F10
SCHEMBL4485218 0.81 F10 (0.83) F10
SCHEMBL4485424 0.81 F10 (1.00) F10
SCHEMBL4481168 0.81 F10 (1.00) F10
SCHEMBL4463987 0.81 F10 (1.00) F10
SCHEMBL4493114 0.80 F10 (1.00) F10
SCHEMBL4481325 0.77 F10 (1.00) F10
SCHEMBL6986900 0.76 PSEN1 (0.51) F10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1501798-A4 SULFONYLAMINOVALEROLAC TAMS AND DERIVATIVES THEREOF AS FACTOR Xa INHIBITORS BRISTOL MYERS SQUIBB CO (US) 2006-11-22 EP disclosed
EP-1501798-A2 SULFONYLAMINOVALEROLAC TAMS AND DERIVATIVES THEREOF AS FACTOR Xa INHIBITORS Bristol-Myers Squibb Company (US) 2005-02-02 EP disclosed
WO-2004041776-A2 SULFONYLAMINOVALEROLAC TAMS AND DERIVATIVES THEREOF AS FACTOR Xa INHIBITORS BRISTOL-MYERS SQUIBB COMPANY (US) 2004-05-21 WO disclosed