Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.61 |
| ▸ | RAB9A | P51151 | 3/20 | 0.61 |
| ▸ | NPC1 | O15118 | 2/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.59 |
| ▸ | GRIN2B | Q13224 | 9/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.52 |
| ▸ | FAAH | O00519 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.50 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19221832 | 1.00 | SMN1; SMN2 (0.61) | SMN1; SMN2RAB9ANPC1CYP2C19GRIN2B | |
| SCHEMBL6773162 | 0.92 | SMN1; SMN2 (0.55) | SMN1; SMN2RAB9ANPC1CYP2C19GRIN2B | |
| SCHEMBL1843950 | 0.92 | SMN1; SMN2 (0.55) | SMN1; SMN2RAB9ANPC1CYP2C19GRIN2B | |
| SCHEMBL7700888 | 0.92 | SMN1; SMN2 (0.55) | SMN1; SMN2RAB9ANPC1CYP2C19GRIN2B | |
| SCHEMBL458148 | 0.92 | SMN1; SMN2 (0.68) | SMN1; SMN2RAB9ANPC1CYP2C19GRIN2B | |
| SCHEMBL541346 | 0.89 | SMN1; SMN2 (0.64) | SMN1; SMN2RAB9ANPC1CYP2C19GRIN2B | |
| SCHEMBL3444915 | 0.89 | SMN1; SMN2 (0.64) | SMN1; SMN2RAB9ANPC1CYP2C19GRIN2B | |
| SCHEMBL100555 | 0.89 | SMN1; SMN2 (0.64) | SMN1; SMN2RAB9ANPC1CYP2C19GRIN2B | |
| SCHEMBL3652558 | 0.88 | SMN1; SMN2 (0.61) | SMN1; SMN2RAB9ANPC1CYP2C19GRIN2B | |
| SCHEMBL20187093 | 0.86 | SMN1; SMN2 (0.57) | SMN1; SMN2RAB9ANPC1CYP2C19GRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1667994-A1 | QUINOLONE ANTIBACTERIAL AGENTS | Warner-Lambert Company LLC (US) | 2006-06-14 | — | — | EP | disclosed |
| WO-2005026154-A1 | QUINOLONE ANTIBACTERIAL AGENTS | WARNER-LAMBERT COMPANY LLC (US) | 2005-03-24 | — | — | WO | disclosed |
| WO-2005026165-A1 | QUINOLONE ANTIBACTERIAL AGENTS | WARNER-LAMBERT COMPANY LLC (US) | 2005-03-24 | — | — | WO | disclosed |